MAB3306
Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4
clone 55-2A4, Chemicon®, from mouse
Synonym(s):
Stromelysin-1, Transin, Proteoglycanase
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
55-2A4, monoclonal
species reactivity
human, pig, rat, sheep
should not react with
bovine, rabbit, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... MMP3(4314)
Specificity
The antibody specifically reacts with precursor and active forms of human MMP-3. This is a purified mouse monoclonal antibody to human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells. The antibody cross reacts 34% with human MMP-10.
Immunogen
Epitope: cross reacts w/hMMP-10
Human matrix metalloproteinase 3 (human MMP-3, stromelysin-1) from synovial cells.
Application
Immunoblotting (0.5 μg/mL)
Immunohistochemistry on paraffin-embedded tissues (5-10μg/mL, PLP fixation required, not recommended for traditional formalin fixation. Immunohistochemistry on fresh frozen sections (0.5 μg/mL)
ElA
Immunohistochemistry on paraffin-embedded tissues (5-10μg/mL, PLP fixation required, not recommended for traditional formalin fixation. Immunohistochemistry on fresh frozen sections (0.5 μg/mL)
ElA
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
This Anti-MMP-3 Antibody, cross reacts w/hMMP-10, clone 55-2A4 is validated for use in ELISA, WB, IH(P) for the detection of MMP-3.
Physical form
Format: Purified
Liquid in 0.01M Na-Phosphate buffer, pH 7.0, 125 mM NaCl, containing 2% protease free bovine serum albumin.
Storage and Stability
Maintain frozen at -20°C in undiluted aliquots for up to 12 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Manufactured by Daiichi Fine Chemical Co., Ltd
Manufactured by Daiichi Fine Chemical Co., Ltd
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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K Obata et al.
Clinica chimica acta; international journal of clinical chemistry, 211(1-2), 59-72 (1992-10-15)
A one-step sandwich enzyme immunoassay (EIA) for matrix metalloproteinase 3 (MMP-3; stromelysin-1) was developed. The assay system used two simultaneous immunoreactions using a solid phase monoclonal antibody and a horseradish peroxidase-labeled monoclonal antibody (Fab'). The sensitivity of the assay system
Christelle Sanchez et al.
Arthritis and rheumatism, 64(4), 1193-1203 (2011-10-29)
Recent data have shown that abnormal subchondral bone remodeling plays an important role in osteoarthritis (OA) onset and progression, and it was suggested that abnormal mechanical pressure applied to the articulation was responsible for these metabolic changes. This study was
Genomic and proteomic profiling of oxidative stress response in human diploid fibroblasts.
Lifang Xie, Ritu Pandey, Beibei Xu, George Tsaprailis, Qin M Chen, Lifang Xie et al.
Biogerontology null
Iraklis Papageorgiou et al.
Nanomaterials (Basel, Switzerland), 4(2), 485-504 (2014-06-16)
Medical interventions for the treatment of spinal disc degeneration include total disc replacement and fusion devices. There are, however, concerns regarding the generation of wear particles by these devices, the majority of which are in the nanometre sized range with
Journal of dental research
Ogbureke, KU; Fisher, LW
Journal of Dental Research null
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