CBL243
Anti-Glucose Transporter GLUT-4 Antibody
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... SLC2A4(6517)
Specificity
Specific for human glucose transporter-4 from muscle and adipose tissue. The antisera does not cross-react with GLUT-1. The molecular weight of the glucose transporter precipitated by the serum is approximately 46 kDa.
Immunogen
Partially purified GLUT-4
Application
Research Category
Signaling
Signaling
Research Sub Category
Insulin/Energy Signaling
Insulin/Energy Signaling
This Anti-Glucose Transporter GLUT-4 Antibody is validated for use in IP, WB for the detection of Glucose Transporter GLUT-4.
Western blot analysis of GLUT-4 activity in adipose and muscle tissue (5μg/ml)
Immunoprecipitation of GLUT-4 (5μg/ml)
Optimal working dilutions must be determined by the end user.
Immunoprecipitation of GLUT-4 (5μg/ml)
Optimal working dilutions must be determined by the end user.
Target description
46 kDa
Physical form
ImmunoAffinity Purified
Purified immunoglobulin in PBS with 0.01% sodium azide.
Storage and Stability
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
Analysis Note
Control
Positive Control: 3T3 L1 adipocyte membranes
Positive Control: 3T3 L1 adipocyte membranes
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Description
Pricing
Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.
Russo, GT; Minutoli, L; Bitto, A; Altavilla, D; Alessi, E; Giandalia, A; Romeo et al.
Journal of Nutrition and Metabolism null
Preventing the calorie restriction-induced increase in insulin-stimulated Akt2 phosphorylation eliminates calorie restriction's effect on glucose uptake in skeletal muscle.
Sharma, N; Arias, EB; Sequea, DA; Cartee, GD
Biochimica et Biophysica Acta null
The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism.
Szekeres, F; Chadt, A; Tom, RZ; Deshmukh, AS; Chibalin, AV; Bjornholm, M; Al-Hasani, H; Zierath, JR
American Journal of Physiology. Endocrinology and Metabolism null
Exercise restores insulin, but not adiponectin, response in skeletal muscle of high-fat fed rodents.
Roberto A Gulli et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 303(10), R1062-R1070 (2012-10-12)
High-fat (HF) diets impair skeletal muscle response to the insulin-sensitizing adipokine adiponectin (Ad) in rodents, preceding the development of insulin resistance. Skeletal muscle insulin response in HF-fed rats can be restored with chronic exercise; whether recovery of skeletal muscle Ad
Xiaohua Zheng et al.
PloS one, 15(2), e0223340-e0223340 (2020-02-14)
The Rab GTPase activating protein known as Akt substrate of 160 kDa (AS160 or TBC1D4) regulates insulin-stimulated glucose uptake in skeletal muscle, the heart, and white adipose tissue (WAT). A novel rat AS160-knockout (AS160-KO) was created with CRISPR/Cas9 technology. Because
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