AB9208
Anti-DARPP-32 Antibody, phosphoThr75
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PPP1R1B(84152)
Specificity
DARPP-32, phosphoThr75.
Immunogen
Epitope: phosphoThr75
Synthetic peptide from human/mouse DARPP-32, phosphoThr75.
Application
Detect DARPP-32 using this Anti-DARPP-32 Antibody, phosphoThr75 validated for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Reward & Addiction
Signaling Neuroscience
Reward & Addiction
Signaling Neuroscience
Western blot: 1:1,000. The antibody recognizes the ~34 kD DARPP-32 protein phosphorylated at Thr75 protein in rat caudate lysate prepared from caudate slices that had been incubated in the absence and presence of okadaic acid. The labeling by the antibody to DARPP-32 Thr75 is markedly increased by the okadaic acid treatment.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg per mL BSA with 50% glycerol.
Storage and Stability
Maintain at -20°C to -80°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Bruno R Souza et al.
Cellular and molecular neurobiology, 31(1), 135-143 (2010-09-15)
It is well known that dopamine imbalances are associated with many psychiatric disorders and that the dopaminergic receptor D₂ is the main target of antipsychotics. Recently it was shown that levels of two proteins implicated in dopaminergic signaling, Neuronal calcium
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