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AB1745

Sigma-Aldrich

Anti-Connexin 45 Antibody, near CT, cytoplasmic

Chemicon®, from rabbit

Synonym(s):

Cx45

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human, mouse

species reactivity (predicted by homology)

dog (based on 100% sequence homology)

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

UniProt accession no.

P36383

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

dog ... Gjc1(490936)
human ... GJC1(10052)
mouse ... Gjc1(14615)
rat ... Gjc1(266706)

Specificity

Recognizes Human, rat and mouse Connexin 45. Due to sequence homologies, this antibody is also expected to react with canine (100% homology) Connexin 45. Other species not tested.

Immunogen

KLH-conjugated synthetic, linear peptide corresponding to human Connexin 45 near the C-terminus.

Application

Detect Connexin 45 using this Anti-Connexin 45 Antibody, near C-terminus, cytoplasmic validated for use in IP, WB, IH.

Physical form

Format: Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Spatially and temporally distinct expression of fibroblast connexins after sheep ventricular infarction.
Camelliti, P; Devlin, GP; Matthews, KG; Kohl, P; Green, CR
Cardiovascular Research null
X Li et al.
American journal of physiology. Heart and circulatory physiology, 281(5), H1890-H1898 (2001-10-23)
Cells in blood vessel walls express connexin (Cx)43, Cx40, and Cx37. We recently characterized gap junction channels in rat basilar artery smooth muscle cells and found features attributable not only to these three connexins but also to an unidentified connexin
J A Cancelas et al.
Blood, 96(2), 498-505 (2000-07-11)
Gap junctions (GJs) provide for a unique system of intercellular communication (IC) allowing rapid transport of small molecules from cell to cell. GJs are formed by a large family of proteins named connexins (Cxs). Cx43 has been considered as the
Characteristics of cultured subepithelial fibroblasts in the rat small intestine. II. Localization and functional analysis of endothelin receptors and cell-shape-independent gap junction permeability.
Sonoko Furuya, Kishio Furuya, Masahiro Sokabe, Takeshi Hiroe, Tsuyoshi Ozaki
Cell and Tissue Research null
M Nitta et al.
Journal of animal science, 88(10), 3269-3279 (2010-06-22)
During mammalian oogenesis, intercellular communication between oocytes and the surrounding follicle cells through gap junction channels is crucial for oocyte development and maturation. The channel properties of gap junctions may be affected by the composition or combination of connexins, the
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