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O-006

Supelco

Oxycodone-D3 solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C18H18NO4D3
CAS Number:
Molecular Weight:
318.38
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

O[C@]1([C@H](N(C)CC2)C3)[C@@]42C5=C3C=CC(OC([2H])([2H])[2H])=C5O[C@H]4C(CC1)=O

InChI

1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1/i2D3

InChI key

BRUQQQPBMZOVGD-CLILCLBHSA-N

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General description

This internal standard is suited for quantification of oxycodone levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, forensic analysis, or isotope dilution methods. Oxycodone is a semi-synthetic opioid analgesic sold under many trade names including OxyContin® and Percocet® for treatment of moderate to severe pain. Oxycodone is also sold illicitly under street names such as "Roxies," "Blues," and "Perks".

Application

  • Pharmacokinetic Analysis: Lu et al. used Oxycodone-D3 in a study to develop a method for the simultaneous determination of acetaminophen and oxycoDonein human plasma, highlighting its utility in pharmacokinetic analysis and as an internal standard in LC-MS/MS assays (Lu et al., 2018).
  • Bioanalytical Method Validation: Bergeron et al. discussed the importance of using high-purity internal standards like Oxycodone-D3 for successful bioanalytical assays, emphasizing its role in improving the accuracy and reliability of liquid chromatography/tandem mass spectrometric analyses (Bergeron et al., 2009).
  • Postmortem Distribution: Anderson et al. explored the postmortem tissue distribution of oxycodone, using Oxycodone-D3 to trace its levels in various tissues, which is crucial for forensic toxicology and understanding the drug′s behavior in the human body after death (Anderson et al., 2002).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
OxyContin is a registered trademark of Purdue Pharma L.P.
Percocet is a registered trademark of Endo Pharmaceuticals Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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