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A-921

Supelco

7-Aminoflunitrazepam-d7 solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C16D7H7FN3O
CAS Number:
Molecular Weight:
290.34
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland)

concentration

100 μg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

2-8°C

SMILES string

O=C1CN=C(C2=C([2H])C([2H])=C([2H])C([2H])=C2F)C3=C(C=CC(N)=C3)N1C([2H])([2H])[2H]

InChI

1S/C16H14FN3O/c1-20-14-7-6-10(18)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)17/h2-8H,9,18H2,1H3/i1D3,2D,3D,4D,5D

InChI key

LTCDLGUFORGHGY-AAYPNNLASA-N

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General description

This stable-labeled internal standard is suitable for quantitation of 7-aminoflunitrazepam levels in GC/MS or LC/MS methods for clinical toxicology, forensic analysis, urine drug testing, pain prescription monitoring or isotope dilution applications. 7-Aminoflunitrazepam is a major urinary metabolite of flunitrazepam, sold under the trade name Rohypnol. Flunitrazepam is an intermediate-acting benzodiazepine prescribed for the treatment of severe insomnia.

Application

  • Use in Forensic Toxicology: The application of 7-Aminoflunitrazepam-d7 as an analytical standard in forensic toxicology is suggested due to its stable isotope labeling, enhancing the accuracy of detecting benzodiazepine metabolites in biological samples. This application supports precise quantitative analysis in forensic cases (Decundo et al., 2024).
  • Internal Standard for LC-MS/MS: 7-Aminoflunitrazepam-d7 is valuable as an internal standard for LC-MS/MS in the analysis of complex biological matrices. Its use improves the reliability of pharmacokinetic studies of benzodiazepines, providing essential data for both clinical and research settings (Mandal et al., 2024).
  • Research in Benzodiazepine Metabolism: High-purity 7-Aminoflunitrazepam-d7 is crucial for the study of benzodiazepine metabolism, particularly in understanding the pharmacokinetic profiles of these drugs. The stable isotope-labeled compound aids in detailed metabolite analysis, contributing to safer drug design and therapeutic monitoring (Johnson et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

wgk_germany

WGK 2

flash_point_f

35.6 °F

flash_point_c

2 °C


Certificates of Analysis (COA)

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