Skip to Content
MilliporeSigma
All Photos(1)

Documents

870851P

Avanti

C16 Carnitine

Avanti Polar Lipids 870851P, powder

Synonym(s):

palmitoyl L-carnitine

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C23H45NO4
CAS Number:
1935-18-8
Molecular Weight:
399.61
UNSPSC Code:
12352211
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 5 mg (870851P-5mg)

manufacturer/tradename

Avanti Polar Lipids 870851P

lipid type

bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3

InChI key

XOMRRQXKHMYMOC-UHFFFAOYSA-N

General description

C16 Carnitine, also called as palmitoyl L-carnitine, is an endogenous acylcarnitine. Structurally, it contains Levocarnitine (L-carnitine) head group and 16 carbon saturated fatty acid tail. Palmitoyl L-carnitine is derived by reversible reaction of palmitoyl-CoA esters with carnitine. Palmitoyl L-carnitine is transported across the inner membrane by carnitine palmitoyl transferase II for β-oxidation.

Application

C16 Carnitine or palmitoyl L-carnitine has been used to study its influence on the glycine transporters activity.

Biochem/physiol Actions

C16 Carnitine has a potential to inhibit glycine transporter 2 (GlyT2). It acts as a key energy donor for β-oxidation. Palmitoyl carnitine activates the Ca2+ release channel of skeletal muscle sarcoplasmic reticulum. Elevated levels of palmitoyl L-carnitine due to palmitoyl transferase II deficiency causes autosomal recessive disorder of energy metabolism, which primarily affects skeletal muscle.

Packaging

5 mL Amber Glass Screw Cap Vial (870851P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

R el-Hayek et al.
Biophysical journal, 65(2), 779-789 (1993-08-01)
Studies of [3H]ryanodine binding, 45Ca2+ efflux, and single channel recordings in planar bilayers indicated that the fatty acid metabolite palmitoyl carnitine produced a direct stimulation of the Ca2+ release channel (ryanodine receptor) of rabbit and pig skeletal muscle junctional sarcoplasmic

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service