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860345P

Avanti

14:0 PC-d54

1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine, powder

Synonym(s):

DMPC-D54

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About This Item

Empirical Formula (Hill Notation):
C36H18NO8PD54
CAS Number:
78415-49-3
Molecular Weight:
732.27
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (860345P-10mg)
pkg of 1 × 100 mg (860345P-100mg)
pkg of 1 × 200 mg (860345P-200mg)
pkg of 1 × 25 mg (860345P-25mg)

manufacturer/tradename

Avanti Polar Lipids 860345P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H])C([2H])([2H])C([2H])([2H

InChI

1S/C36H72NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-35(38)42-32-34(33-44-46(40,41)43-31-30-37(3,4)5)45-36(39)29-27-25-23-21-19-17-15-13-11-9-7-2/h34H,6-33H2,1-5H3/t34-/m1/s1/i1D3,2D3,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2,22D2,23D2,24D2,25D2,26D2,27D2,28D2,29D2

InChI key

CITHEXJVPOWHKC-RPLUSTTMSA-N

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Phosphocholine is a metabolic intermediate of phosphatidylcholine synthesis. Phosphorylation of choline in the presence of ATP yield phosphocholine.

Application

14:0 PC-d54 is suitable to reconstitute [ILV-13CH3, U-15N, 2H] labeled EmrE in n-dodecyl-β-D-maltopyranoside (DDM) back-exchanged to 1H at the amide positions during nuclear magnetic resonance (NMR) sample preparation. It is also suitable for the preparation of phospholipid liposomes.

Packaging

5 mL Amber Glass Screw Cap Vial (860345P-100mg)
5 mL Amber Glass Screw Cap Vial (860345P-10mg)
5 mL Amber Glass Screw Cap Vial (860345P-200mg)
5 mL Amber Glass Screw Cap Vial (860345P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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Description
Pricing

Storage Class

11 - Combustible Solids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Phosphatidylcholine and the CDP-Choline Cycle
Fagone P, et al.
Biochimica et Biophysica Acta, 1831(5) (2013)
Jess Li et al.
The Journal of biological chemistry, 295(9), 2664-2675 (2020-01-25)
Engineering and bioconjugation of proteins is a critically valuable tool that can facilitate a wide range of biophysical and structural studies. The ability to orthogonally tag or label a domain within a multidomain protein may be complicated by undesirable side
Alessio Ausili et al.
Langmuir : the ACS journal of surfaces and colloids, 36(4), 1062-1073 (2020-01-14)
Vitamin K1 and vitamin K2 play very important biological roles as members of chains of electron transport as antioxidants in membranes and as cofactors for the posttranslational modification of proteins that participate in a number of physiological functions such as
Protonation of a glutamate residue modulates the dynamics of the drug transporter EmrE
Gayen A, et al.
Nature chemical biology, 12(3), 141-141 (2016)
Fusion of Legionella pneumophila outer membrane vesicles with eukaryotic membrane systems is a mechanism to deliver pathogen factors to host cell membranes
Jager J, et al.
Cellular Microbiology, 17(5), 607-620 (2015)
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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