855810P
Avanti
26:0 Lyso PC
1-hexacosanoyl-2-hydroxy-sn-glycero-3-phosphocholine, powder
Synonym(s):
1-hexacosanoyl-sn-glycero-3-phosphocholine; PC(26:0/0:0)
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C34H70NO7P
CAS Number:
Molecular Weight:
635.90
UNSPSC Code:
51191904
NACRES:
NA.25
Recommended Products
assay
>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)
form
powder
packaging
pkg of 1 × 10 mg (855810P-10mg)
pkg of 1 × 25 mg (855810P-25mg)
pkg of 1 × 5 mg (855810P-5mg)
manufacturer/tradename
Avanti Polar Lipids 855810P
shipped in
dry ice
storage temp.
−20°C
General description
Lysophosphatidylcholine (LPC) is a bioactive proinflammatory lipid, which has a choline group at its polar head. It is produced by pathological response.
Application
26:0 Lyso PC has been used as an internal standard for C26:0-lysophosphatidylcholine (LPC) extraction.
Biochem/physiol Actions
Lysophosphatidylcholine (LPC) induces many second messengers including, protein kinase C, extracellular-signal-regulated kinases and protein tyrosine kinases. It alters various biological functions in different cell types, including endothelial cells, smooth muscle cells, monocytes, macrophages and T-cells. LPC is linked to atherosclerosis and inflammatory diseases.
Packaging
5 mL Amber Glass Screw Cap Vial (855810P-10mg)
5 mL Amber Glass Screw Cap Vial (855810P-25mg)
5 mL Amber Glass Screw Cap Vial (855810P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Xinying Hong et al.
Genetics in medicine : official journal of the American College of Medical Genetics (2020-04-21)
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Hartley MD, et al.
Endocrinology, 158(5), 1328-1338 (2017)
Analysis of phospholipid species in rat peritoneal surface layer by liquid chromatography/electrospray ionization ion-trap mass spectrometry
Gao F, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1761(7), 667-676 (2006)
Kelsey B Law et al.
Autophagy, 13(5), 868-884 (2017-05-20)
Peroxisome biogenesis disorders (PBDs) are metabolic disorders caused by the loss of peroxisomes. The majority of PBDs result from mutation in one of 3 genes that encode for the peroxisomal AAA ATPase complex (AAA-complex) required for cycling PEX5 for peroxisomal
Role of lysophosphatidylcholine (LPC) in atherosclerosis
Matsumoto T, et al.
Current Medicinal Chemistry, 14(30), 3209-3220 (2007)
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