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850365C

Avanti

18:0 PC (DSPC)

Avanti Polar Lipids

Synonym(s):

1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)

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About This Item

Empirical Formula (Hill Notation):
C44H88NO8P
CAS Number:
816-94-4
Molecular Weight:
790.15
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-distearoyl-sn-glycero-3-phosphocholine, chloroform

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (850365C-25mg)
pkg of 1 × 20 mL (850365C-500mg)
pkg of 2 × 20 mL (850365C-1g)
pkg of 2 × 4 mL (850365C-200mg)

manufacturer/tradename

Avanti Polar Lipids

concentration

10 mg/mL (850365C-25mg)
25 mg/mL (850365C-1g)
25 mg/mL (850365C-200mg)
25 mg/mL (850365C-500mg)

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChI key

NRJAVPSFFCBXDT-HUESYALOSA-N

General description

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:0 PC (DSPC) has been used in the preparation of microbubbles (MBs). It is suitable for use in the synthesis of methylene blue (MB)-liposome synthesis and in the preparation of unilamellar vesicles

Biochem/physiol Actions

18:0 PC (DSPC) liposomes/1,2-Dioctadecanoyl-sn-glycero-3-phosphocholine, along with Rhamnolipids (RLs) can serve as the best combination for drug delivery application. It can help to maintain the stability of curcumin.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-1g)
30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (850365C-500mg)
5 mL Clear Glass Sealed Ampule (850365C-200mg)
5 mL Clear Glass Sealed Ampule (850365C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

also commonly purchased with this product

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700000P

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16:0-18:1 PS (POPS), Avanti Polar Lipids

850345C

14:0 PC (DMPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine, chloroform

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16:0 PC (DPPC), Avanti Polar Lipids

850368C

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, chloroform

850368P

20:0 PC, 1,2-diarachidoyl-sn-glycero-3-phosphocholine, powder

850373C

24:0 PC, 1,2-dilignoceroyl-sn-glycero-3-phosphocholine, chloroform

850375C

18:1 (Δ9-Cis) PC (DOPC), Avanti Polar Lipids

850457C

16:0-18:1 PC, Avanti Polar Lipids

850464C

18:0-14:0 PC, 1-stearoyl-2-myristoyl-sn-glycero-3-phosphocholine, chloroform

850467C

18:0-18:1 PC, 1-stearoyl-2-oleoyl-sn-glycero-3-phosphocholine, chloroform

850757C

16:0-18:1 PE, Avanti Polar Lipids

855675P

16:0 Lyso PC, Avanti Polar Lipids

880120C

18:0 PEG2000 PE, Avanti Polar Lipids 880120C

880129C

DSPE-PEG(2000) Biotin, Avanti Polar Lipids 880129C

610000

Extruder Set with Holder/Heating Block, Avanti Polar Lipids

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_c

does not flash

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Interaction of curcumin with 1, 2-dioctadecanoyl-sn-glycero-3-phosphocholine liposomes: Intercalation of rhamnolipids enhances membrane fluidity, permeability and stability of drug molecule
Moussa Z, et al.
Colloids and Surfaces. B, Biointerfaces, 149, 30-37 (2017)
Methylene-Blue-Encapsulated Liposomes as Photodynamic Therapy Nano Agents for Breast Cancer Cells
Wu PT, et al.
Nanomaterials, 9(1), 14-14 (2019)
Ana Reis et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183133-183133 (2019-12-01)
Food polyphenols in fruits juices, tea, coffee, wine and beer confer sensory properties such as colour, astringency and bitterness. The development of functional healthy drinks without the unpleasant sensory feeling is boosting research for a clearer understanding on the interactions
Tadaharu Suga et al.
Molecular pharmaceutics, 15(10), 4481-4490 (2018-09-05)
High-functionality and -quality (HFQ) lipids have a discrete molecular weight and good water dispersibility and can be produced by solid-phase peptide synthesis. Therefore, HFQ lipids are a promising material for the preparation of ligand-grafted PEGylated liposomes. Recently, we have reported
Liposome layers characterized by quartz crystal microbalance measurements and multirelease delivery
Brochu H and Vermette P
Langmuir, 23(14), 7679-7686 (2007)
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