810288P
Avanti
16:0 TopFluor® cholesterol
Avanti Polar Lipids 810288P, powder
Synonym(s):
23-(dipyrrometheneboron difluoride)-24-norcholesteryl palmitate
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About This Item
Empirical Formula (Hill Notation):
C52H81 BF2N2O2
CAS Number:
Molecular Weight:
815.02
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810288P-1mg)
manufacturer/tradename
Avanti Polar Lipids 810288P
shipped in
dry ice
storage temp.
−20°C
General description
16:0 TopFluor® cholesterol carries saturated acyl chains. Approximately 30-40% of the mammalian plasma membrane consists of cholesterol. TopFluor® has a moiety, called dipyrromethene boron difluoride. This fluorescent molecule is covalently attached to various lipid molecules.
Application
16:0 TopFluor® cholesterol may be used to study its diffusion with phospholipid analogs in model membrane in order to understand cholesterol dynamics at the nanoscale in biomembranes.
Biochem/physiol Actions
Cholesterol participates in various signaling processes. It also helps in shaping the structure of molecular membrane.
Packaging
5 mL Amber Glass Screw Cap Vial (810288P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Nanoscale dynamics of cholesterol in the cell membrane
Pinkwart K, et al.
The Journal of biological chemistry, 294(34), 12599-12609 (2019)
Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate
Shirey CM, et al.
Chemistry and Physics of Lipids, 200, 32-32 (2016)
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