700143P
Avanti
27-alkyne cholesterol
Avanti Polar Lipids 700143P, powder
Synonym(s):
27-alkyne cholesterol
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About This Item
Empirical Formula (Hill Notation):
C28H44O
CAS Number:
Molecular Weight:
396.65
UNSPSC Code:
12352211
NACRES:
NA.25
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assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (700143P-100ug)
pkg of 1 × 250 μg (700143P-250ug)
manufacturer/tradename
Avanti Polar Lipids 700143P
shipped in
dry ice
storage temp.
−20°C
General description
Alkyne cholesterol is used to trace cholesterol metabolism and localization.
This reagent is a modified lipid containing an omega-terminal alkyne. The terminal alkyne group can be used in a highly specific linking reaction with azide-containing reagents, known as ‘click chemistry′, in the presence of a copper (Cu)-containing catalyst.
Biochem/physiol Actions
27-alkyne cholesterol acts similar to natural sterols such as, ergosterol and cholesterol.
Packaging
5 mL Amber Glass Screw Cap Vial (700143P-100ug)
5 mL Amber Glass Screw Cap Vial (700143P-250ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
Certificates of Analysis (COA)
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Kristina Hofmann et al.
Journal of lipid research, 55(3), 583-591 (2013-12-18)
Cholesterol is an important lipid of mammalian cells and plays a fundamental role in many biological processes. Its concentration in the various cellular membranes differs and is tightly regulated. Here, we present a novel alkyne cholesterol analog suitable for tracing
A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization.
Hofmann K, et al.
Journal of Lipid Research, 55(3), 583-591 (2014)
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