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924474

Sigma-Aldrich

Hyaluronic Acid

Low Viscosity, Low endotoxin

Synonym(s):

3D bioprinting, HA, Hyaluronan

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.23

Quality Level

form

(powder or chunk(s) or fibers)

impurities

<10 CFU/g Bioburden
<100 EU/g Endotoxin

color

white to off-white

suitability

conforms to structure for NMR

storage temp.

2-8°C

Related Categories

General description

Hyaluronic acid (HA) is a linear polysaccharide of alternating D-glucuronic acid, and N-acetyl-D-glucosamine found in the extracellular matrix. HA is commonly chemically modified to form covalently crosslinked hydrogels. Other properties of HA include cell surface receptors CD44 and RHAMM recognition and degradation via hyaluronidases.

Application

HA is increasingly used for the following biomedical applications:
  • Cell migration
  • Angiogenesis
  • Viability
  • Proliferation

Our low endotoxin HA is tested for both endotoxin (< 100 EU/g) and bioburden (< 10 CFU/g) levels, so you can choose which material is right for your research.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Tracey J Brown
Current pharmaceutical biotechnology, 9(4), 253-260 (2008-08-12)
Despite advances in chemotherapeutic regimens, the treatment of metastatic cancer remains a challenge. A key problem with chemotherapy drugs is nonspecific drug distribution, resulting in low tumor concentrations and systemic toxicity. The holy grail of clinical cancer research has been
Federica Camin et al.
Journal of agricultural and food chemistry, 58(1), 570-577 (2009-12-17)
H, C, and O stable isotope ratios and the elemental profile of 267 olive oils and 314 surface waters collected from 8 European sites are presented and discussed. The aim of the study was to investigate if olive oils produced
Xian Xu et al.
Soft matter, 8(12), 3280-3294 (2012-03-16)
Hyaluronic acid (HA) is one of nature's most versatile and fascinating macromolecules. Being an essential component of the natural extracellular matrix (ECM), HA plays an important role in a variety of biological processes. Inherently biocompatible, biodegradable and non-immunogenic, HA is
Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits

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