900600
3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid
≥95%
Synonym(s):
Carboxyl sulfonyl fluoride alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C12H13FO4SSi
CAS Number:
Molecular Weight:
300.38
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.22
Recommended Products
assay
≥95%
form
solid
reaction suitability
reagent type: cross-linking reagent
availability
available only in USA
storage temp.
−20°C
SMILES string
O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O
Application
3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
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Description
Pricing
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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