Skip to Content
MilliporeSigma
All Photos(2)

Documents

467006

Sigma-Aldrich

1-Ethynyl-2-fluorobenzene

97%

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
FC6H4C≡CH
CAS Number:
766-49-4
Molecular Weight:
120.12
MDL number:
MFCD00799540
UNSPSC Code:
12352100
PubChem Substance ID:
24870376
NACRES:
NA.22

assay

97%

refractive index

n20/D 1.526 (lit.)

bp

150 °C (lit.)

density

1.06 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

Fc1ccccc1C#C

InChI

1S/C8H5F/c1-2-7-5-3-4-6-8(7)9/h1,3-6H

InChI key

YFPQIXUNBPQKQR-UHFFFAOYSA-N

Related Categories

General description

1-Ethynyl-2-fluorobenzene, a fluorinated benzene derivative, is a terminal alkyne.

Application

1-Ethynyl-2-fluorobenzene has been employed in the cross-coupling of phenylacetylenes. It may be used in the preparation of 3-(2-deoxy-β-D-ribofuranosyl)-6-(2-fluorophenyl)-2,3-dihydrofuro-[2,3-d]pyrimidin-2-one and 4-(2-fluorophenylethynyl)-3-methyl-5-phenylisoxazole.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

98.6 °F - closed cup

flash_point_c

37 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 7

1 of 7

3-Chloro-1-ethynylbenzene 97%

Sigma-Aldrich

630268

3-Chloro-1-ethynylbenzene

2-Ethynylanisole 97%

Sigma-Aldrich

467227

2-Ethynylanisole

4-Ethynyl-α,α,α-trifluorotoluene 97%

Sigma-Aldrich

556432

4-Ethynyl-α,α,α-trifluorotoluene

1-Chloro-4-ethynylbenzene 98%

Sigma-Aldrich

206474

1-Chloro-4-ethynylbenzene

1-Bromo-4-ethynylbenzene 97%

Sigma-Aldrich

206512

1-Bromo-4-ethynylbenzene

Potassium chromium(III) oxalate trihydrate 98%

Sigma-Aldrich

311006

Potassium chromium(III) oxalate trihydrate

Phenylacetylene 98%

Sigma-Aldrich

117706

Phenylacetylene

Synthesis and Biological Evaluation of Novel 1, 2, 3-Triazolonucleotides.
Glowacka IE, et al.
Arch. Pharm. (Weinheim), 346(4), 278-291 (2013)
Synthesis of 3, 4, 5-Trisubstituted Isoxazoles through Gold-Catalyzed Cascade Cyclization- Oxidative Alkynylation and Cyclization-Fluorination of 2-Alkynone O-Methyloximes.
Song D-H and Ryu J-S.
Bull. Korean Chem. Soc., 35(19), 2635-2644 (2014)
Synthesis of Novel 1-Hydroxy-2-(1, 2, 3-triazol-1-yl) ethylphosphonates and 2-Hydroxy-3-(1, 2, 3-triazol-1-yl) propylphosphonates.
Glowacka IE, et al.
Phosphorus, Sulfur, and Silicon and the Related Elements, 186(3), 431-449 (2011)
Tetrahedron Letters, 35, 3689-3689 (1994)
Halophenyl furanopyrimidines as potent and selective anti-VSV agents.
McGuigan C, et al.
Antiviral Chem. Chemother., 14(3), 165-165 (2003)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service