Skip to Content
MilliporeSigma
All Photos(1)

Documents

235881

Sigma-Aldrich

1-Naphthalenesulfonyl chloride

97%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H7ClO2S
CAS Number:
85-46-1
Molecular Weight:
226.68
Beilstein/REAXYS Number:
2099333
EC Number:
201-609-6
MDL number:
MFCD00003984
UNSPSC Code:
12352100
PubChem Substance ID:
24854123
NACRES:
NA.22

Quality Level

100

assay

97%

bp

194-195 °C/13 mmHg (lit.)

mp

64-67 °C (lit.)

solubility

chloroform: soluble 25 mg/mL, clear to very slightly hazy, colorless to yellow

SMILES string

ClS(=O)(=O)c1cccc2ccccc12

InChI

1S/C10H7ClO2S/c11-14(12,13)10-7-3-5-8-4-1-2-6-9(8)10/h1-7H

InChI key

DASJFYAPNPUBGG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

1-Naphthalenesulfonyl chloride undergoes desulfitative carbonylative Stille cross-coupling reaction with tinglucal derivative.

Application

1-Naphthalenesulfonyl chloride has been used in the preparation of:
  • 5′-O-naphthaleneiulfonyldeoxyuridine
  • 1-sulfonylindazole derivatives

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

4-Chlorobenzenesulfonyl chloride 97%

Sigma-Aldrich

133698

4-Chlorobenzenesulfonyl chloride

98%

Sigma-Aldrich

108669

4-Bromobenzenesulfonyl chloride

2-Mesitylenesulfonyl chloride 99%

Sigma-Aldrich

M7707

2-Mesitylenesulfonyl chloride

2,4,6-Triisopropylbenzenesulfonyl chloride 97%

Sigma-Aldrich

119490

2,4,6-Triisopropylbenzenesulfonyl chloride

4-Nitrobenzenesulfonyl chloride 97%

Sigma-Aldrich

272248

4-Nitrobenzenesulfonyl chloride

Kevin G Liu et al.
Bioorganic & medicinal chemistry letters, 19(9), 2413-2415 (2009-04-07)
As part of our continuing efforts to identify therapeutics for CNS diseases, such as schizophrenia and Alzheimer's disease (AD), we have been focused on the 5-HT(6) receptor in an attempt to identify ligands as a potential treatment for cognitive dysfunction.
Aryl and arylmethyl C-glycosides through desulfitative stille and carbonylative stille cross-coupling of tinglycals and sulfonyl chlorides.
Dubbaka SR, et al.
Synlett, 2004(07), 1235-1238 (2004)
A simple method for the synthesis of O2, 5′-cyclodeoxyuridine.
Tang SS and Roth JS.
Tetrahedron Letters, 9(17), 2123-2125 (1968)
Alaa Khedr et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1160, 122383-122383 (2020-09-20)
A sensitive liquid chromatography-tandem mass spectrometry (LC-MS) method was developed for the screening of five β-blockers (BBs), including atenolol, metoprolol, bisoprolol, propranolol, and betaxolol, in rabbit plasma. An inhouse prepared hydrazonoyl chloride compound (UOSA54) and dansyl chloride (DNS) were successfully

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service