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131474

Sigma-Aldrich

1-Phenylpyrrole

99%

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About This Item

Empirical Formula (Hill Notation):
C10H9N
CAS Number:
Molecular Weight:
143.19
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

assay

99%

form

solid

bp

234 °C (lit.)

mp

58-60 °C (lit.)

SMILES string

c1ccc(cc1)-n2cccc2

InChI

1S/C10H9N/c1-2-6-10(7-3-1)11-8-4-5-9-11/h1-9H

InChI key

GEZGAZKEOUKLBR-UHFFFAOYSA-N

General description

1-Phenylpyrrole inhibited cytochrome P-450 dependant monooxygenase activity in microsomes from rat liver.

Application

1-Phenylpyrrole was used to study the half-wave potentials of the aqueous redox couples and the oxidation potentials of the monomers in 1,2-dichloroethane.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Certificates of Analysis (COA)

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Sigma-Aldrich

131709

Pyrrole

T Viswanathan et al.
Journal of medicinal chemistry, 24(7), 822-830 (1981-07-01)
The inhibitions of cytochrome P-450 dependent monooxygenase activity in microsomes from rat liver by 1-phenylpyrrole, 1-(2-isopropylphenyl)pyrrole, 4(5)-phenylimidazole, and 1-(2-isopropylphenyl)imidazole have been compared. The results establish that the presence of an imidazole N-3 nitrogen substituent is not required to inhibit the
Formation of oligomers of methyl-and phenyl-pyrrole at an electrified liquid/liquid interface.
Chemical Communications (Cambridge, England), 19, 2163-2164 (1998)
Kangmin Kim et al.
Journal of the American Chemical Society, 141(15), 6279-6291 (2019-03-28)
Amine-peroxide redox polymerization (APRP) has been highly prevalent in industrial and medical applications since the 1950s, yet the initiation mechanism of this radical polymerization process is poorly understood so that innovations in the field are largely empirically driven and incremental.

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