Skip to Content
MilliporeSigma
All Photos(2)

Documents

119946

Sigma-Aldrich

4-Fluorobenzoyl chloride

98%

Synonym(s):

4-Fluorobenzoic acid chloride, p-Fluorobenzoyl chloride

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
FC6H4COCl
CAS Number:
403-43-0
Molecular Weight:
158.56
Beilstein/REAXYS Number:
386215
EC Number:
206-961-4
MDL number:
MFCD00000684
UNSPSC Code:
12352100
PubChem Substance ID:
24847304

Quality Level

200

assay

98%

refractive index

n20/D 1.532 (lit.)

bp

82 °C/20 mmHg (lit.)

mp

10-12 °C (lit.)

density

1.342 g/mL at 25 °C (lit.)

SMILES string

Fc1ccc(cc1)C(Cl)=O

InChI

1S/C7H4ClFO/c8-7(10)5-1-3-6(9)4-2-5/h1-4H

InChI key

CZKLEJHVLCMVQR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

4-Fluorobenzoyl chloride undergoes Friedel-Crafts acylation reaction with 2,6-dimethylnaphthalene to give 1,5-bis(4-fluorobenzoyl)-2,6-dimethylnaphthalene.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H314

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible, corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

179.6 °F - closed cup

flash_point_c

82 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 5

1 of 5

4-tert-Butylbenzoyl chloride 98%

Sigma-Aldrich

157120

4-tert-Butylbenzoyl chloride

o-Toluoyl chloride 99%

Sigma-Aldrich

122017

o-Toluoyl chloride

4-Fluorobenzyl bromide 97%

Sigma-Aldrich

209538

4-Fluorobenzyl bromide

4-Nitrobenzoyl chloride 98%

Sigma-Aldrich

112208

4-Nitrobenzoyl chloride

2-Iodobenzoyl chloride 98%

Sigma-Aldrich

252115

2-Iodobenzoyl chloride

New multiblock copolymers of sulfonated poly (4'-phenyl-2, 5-benzophenone) and poly (arylene ether sulfone) for proton exchange membranes. II.
Ghassemi H, et al.
Polymer, 45(17), 5855-5862 (2004)
Synthesis of [18F] GBR 12909, a dopamine reuptake inhibitor.
Haka MS and Kilbourn MR.
Journal of Labelled Compounds & Radiopharmaceuticals, 28(7), 793-799 (1990)
Synthesis of a novel naphthalene-based poly (arylene ether-ketone) by polycondensation of 1, 5-bis (4-fluorobenzoyl)-2, 6-dimethylnaphthalene with bisphenol A.
Ohno M, et al.
Journal of Polymer Science Part A: Polymer Chemistry, 33(15), 2647-2655 (1995)
Solid-phase Friedel-Crafts acylation on polystyrene resins-synthesis of antiepiletic 1-aryl-3, 5-dihydro-4H-2, 3-benzodiazepin-4-ones.
Bevacqua F, et al.
Tetrahedron Letters, 42(43), 7683-7685 (2001)
Novel electroactive aromatic polyamide with oligoanilines and azo groups in the backbone: synthesis, characterization and dielectric properties.
He L, et al.
Journal of Polymer Research, 19(1), 1-9 (2012)
View All Related Papers

Articles

Friedel–Crafts Acylation

The Friedel–Crafts acylation is the reaction of an arene with acyl chlorides or anhydrides using a strong Lewis acid catalyst. This reaction proceeds via electrophilic aromatic substitution to form monoacylated products.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service