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Merck

A PIP Gets the plasmodium protein export pathway going.

Cell host & microbe (2012-02-22)
Rays H Y Jiang, Matthias Marti
ABSTRACT

Survival of blood stage malaria parasites requires extensive host cell remodeling, which is facilitated by secretion of parasite proteins via a dedicated protein export pathway. In a recent Cell paper, Bhattacharjee et al., (2012) describe PI(3)P binding as one of the first steps in targeting parasite proteins to the host cell.

MATERIALS
Product Number
Brand
Product Description

Avanti
06:0 PI(3,4,5)P3, 1,2-dihexanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder
Avanti
18:1 PI(3,4,5)P3, 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder
Avanti
08:0 PI(3,4,5)P3, 1,2-dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder