1067704
USP
Betamethasone dipropionate
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
Betamethasone 17,21-dipropionate, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 17,21-dipropionate
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About This Item
Empirical Formula (Hill Notation):
C28H37FO7
CAS Number:
Molecular Weight:
504.59
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
pharmaceutical primary standard
API family
betamethasone
manufacturer/tradename
USP
application(s)
pharmaceutical (small molecule)
format
neat
SMILES string
[H][C@@]12C[C@H](C)[C@](OC(=O)CCl)(C(=O)COC(=O)CC)[C@@]1(C)C[C@H](O)C3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
InChI
1S/C27H34ClFO7/c1-5-22(33)35-14-21(32)27(36-23(34)13-28)15(2)10-19-18-7-6-16-11-17(30)8-9-24(16,3)26(18,29)20(31)12-25(19,27)4/h8-9,11,15,18-20,31H,5-7,10,12-14H2,1-4H3/t15-,18-,19-,20-,24-,25-,26?,27-/m0/s1
InChI key
UOCNBCVPZWLUKX-HOBFILNXSA-N
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General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
- Efficacy in Alopecia Areata Treatment: A study compared the effectiveness of topical betamethasone dipropionate with minoxidil in treating alopecia areata, highlighting its potent anti-inflammatory properties and its role in promoting hair regrowth. This positions betamethasone dipropionate as a key component in dermatological research aimed at understanding and improving treatment modalities for hair loss conditions (Aslam et al., 2024).
- Post-Surgical Pain Management: Research demonstrated the utility of a cocktail containing betamethasone dipropionate in reducing pain and prolonging analgesic effects post-total knee arthroplasty. This study emphasizes the pharmacokinetic benefits of betamethasone dipropionate in clinical pain management, providing valuable insights for ongoing pharmacological innovations (Luo et al., 2024).
- Improvement in Plaque Psoriasis: Betamethasone dipropionate was analyzed for its effectiveness in treating plaque psoriasis when used as part of a calcipotriol/betamethasone aerosol foam. The results underscore its significant role as a glucocorticoid receptor agonist, enhancing therapeutic outcomes for patients with psoriasis, thereby solidifying its place in anti-inflammatory steroid studies and psoriasis treatment compounds (Gerdes et al., 2024).
Biochem/physiol Actions
Betamethasone 17,21-dipropionate is a glucocorticoid with anti-inflammatory and immunosuppressive activity.
Analysis Note
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Other Notes
Sales restrictions may apply.
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Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Repr. 1B - STOT RE 2
Target Organs
Liver,Kidney,Endocrine system
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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