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47858

Supelco

Thiamine Hydrochloride (B1)

analytical standard

Synonym(s):

Thiamine hydrochloride, Aneurine hydrochloride, Vitamin B1 hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C12H17ClN4OS · HCl
CAS Number:
67-03-8
Molecular Weight:
337.27
Beilstein:
3851771
EC Number:
200-641-8
MDL number:
MFCD00012780
UNSPSC Code:
12164500
PubChem Substance ID:
24871525

grade

analytical standard

CofA

current certificate can be downloaded

feature

standard type water soluble vitamin

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

250 °C (dec.) (lit.)

application(s)

pharmaceutical (small molecule)
vitamins, nutraceuticals, and natural products

format

neat

storage temp.

2-30°C

SMILES string

CC1=NC(N)=C(C[N+]2=CSC(CCO)=C2C)C=N1.Cl.[Cl-]

InChI

1S/C12H17N4OS.2ClH/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13;;/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15);2*1H/q+1;;/p-1

InChI key

DPJRMOMPQZCRJU-UHFFFAOYSA-M

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General description

Thiamine hydrochloride (B1) is a water soluble vitamin, which belongs the B-complex group of vitamins. It can exist both as a hemihydrate and as a nonstoichiometric hydrate. It can generally act like a co-enzyme for biochemical reactions involved in carbohydrate metabolism.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Thiamine Hydrochloride (B1) may be used as an analytical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography (HPLC) technique.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD4069
LRAD0313
LRAC8351
LRAC2207
LRAC0060

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Sigma-Aldrich

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Thiamine hydrochloride

Thiamine hydrochloride meets USP testing specifications

Sigma-Aldrich

T4562

Thiamine hydrochloride

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Thiamine hydrochloride tested according to Ph. Eur.

Sigma-Aldrich

04573

Thiamine hydrochloride

Wanamaker.PB and Massey K
Applied Pharmacology for Veterinary Technicians, (5) (2014)
Insights into the dehydration behavior of thiamine hydrochloride (Vitamin B1) hydrates: Part II
Chakravarty P, et al.
Journal of Pharmaceutical Sciences, 99(4), 1882-1895 (2010)
High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection
Marszall LM, et al.
Journal of Chromatography A, 1094(1-2), 91-98 (2005)
Josefin Engelhardt et al.
PloS one, 15(1), e0227201-e0227201 (2020-01-03)
The eastern Baltic cod (Gadus morhua) population has been decreasing in the Baltic Sea for at least 30 years. Condition indices of the Baltic cod have decreased, and previous studies have suggested that this might be due to overfishing, predation
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Alcoholism, clinical and experimental research, 38(7), 2127-2137 (2014-06-17)
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