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V6627

Sigma-Aldrich

Anti-Vascular Endothelial Growth Factor antibody produced in goat

IgG fraction of antiserum, lyophilized powder

Synonym(s):

Anti-VEGF

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About This Item

MDL number:
MFCD00282511
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

goat

Quality Level

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5-15 μg/mL
neutralization: suitable
western blot: 1-2 μg/mL

UniProt accession no.

P15692

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... VEGFA(7422)

Specificity

The antibody will neutralize the biological activity of recombinant human VEGF165 and recombinant human VEGF121. The antibody shows ~20% cross-reactivity with recombinant mouse VEGF and recombinant rat VEGF.

Immunogen

recombinant human VEGF.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Preparation Note

Purified using protein G.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Markus Theurl et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 32(9), 4815-4823 (2018-06-20)
The pathogenesis of diabetic neuropathy remains enigmatic. Damage to the vasa nervorum may be responsible for this disorder. Recently, we showed that secretoneurin (SN) induces angiogenesis in hindlimb and myocardial ischemia. Moreover, beneficial effects were observed in wound healing. We
Henning Ulrich et al.
Frontiers in pharmacology, 9, 500-500 (2018-06-06)
Bone marrow metastasis occurs in approximately 350,000 patients that annually die in the U.S. alone. In view of the importance of tumor cell migration into the bone marrow, we have here investigated effects of various concentrations of stromal cell-derived factor-1
Cheuk-Lun Lee et al.
Human reproduction (Oxford, England), 34(4), 689-701 (2019-01-01)
Does glycodelin-A (GdA) induce conversion of human peripheral blood CD16-CD56bright natural killer (NK) cells to decidual NK (dNK) cells to facilitate placentation? GdA binds to blood CD16-CD56bright NK cells via its sialylated glycans and converts them to a dNK-like cells
Indu Sharma et al.
Fertility and sterility, 94(5), 1639-1646 (2009-12-01)
To investigate the in vitro effects of atorvastatin on lipopolysaccharide (LPS)-induced gene expression in endometrial-endometriotic stromal cells. In vitro experimental study using flow cytometry, ELISA, semiquantitative reverse transcriptase polymerase chain reaction, and Western blot. Postgraduate Institute of Medical Education and
Lei Li et al.
Oncology letters, 16(5), 5645-5654 (2018-10-23)
Non-small cell lung cancer (NSCLC) is the most common cause of cancer-associated mortality worldwide. Prostaglandin E2 (PGE2) regulates various biological processes, including invasion, proliferation and apoptosis. E-prostanoid 3 (Ep3) is a PGE2 receptor, and the functional role of Ep3 in
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