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PZ0103

Sigma-Aldrich

CP-346086 dihydrate

≥97% (HPLC)

Synonym(s):

4′-Trifluoromethyl-biphenyl-2-carboxylic acid [2-(2H-[1,2,4]triazol-3-ylmethyl)-1,2,3,4-tetrahydro-isoquinolin-6-yl]amide dihydrate

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About This Item

Empirical Formula (Hill Notation):
C26H22F3N5O · 2H2O
CAS Number:
Molecular Weight:
513.51
MDL number:
UNSPSC Code:
41106200
PubChem Substance ID:
NACRES:
NA.77

Quality Level

Assay

≥97% (HPLC)

form

powder

color

white to beige

solubility

DMSO: >20 mg/mL

storage temp.

2-8°C

SMILES string

O.O.FC(F)(F)c1ccc(cc1)-c2ccccc2C(=O)Nc3ccc4CN(CCc4c3)Cc5ncn[nH]5

InChI

1S/C26H22F3N5O.2H2O/c27-26(28,29)20-8-5-17(6-9-20)22-3-1-2-4-23(22)25(35)32-21-10-7-19-14-34(12-11-18(19)13-21)15-24-30-16-31-33-24;;/h1-10,13,16H,11-12,14-15H2,(H,32,35)(H,30,31,33);2*1H2

InChI key

QCUKFGSPPGIYIX-UHFFFAOYSA-N

Biochem/physiol Actions

CP-346086 is microsomal triglyceride transfer protein (MTP, MTTP) inhibitor.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Protocols

The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate.

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