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N8035

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide phosphate sodium salt

pkg of 5 mg (per vial)

Synonym(s):

β-NADP-Na, β-NADP-sodium salt, Coenzyme II sodium salt, NADP, TPN, TPN-Na, Triphosphopyridine nucleotide sodium salt

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About This Item

Linear Formula:
C21H27N7O17P3 · Na
CAS Number:
1184-16-3
Molecular Weight:
765.39
Beilstein:
4779954
EC Number:
214-664-6
MDL number:
MFCD00036973
UNSPSC Code:
41106305
PubChem Substance ID:
24897850
NACRES:
NA.51

form

powder

Quality Level

200

packaging

pkg of 5 mg (per vial)

mp

175-178 °C (dec.) (lit.)

storage temp.

−20°C

SMILES string

[Na+].[H]O[H].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@@H]([C@@H]3O)P(O)(O)=O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H28N7O16P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(45(33,34)35)14(30)11(43-21)6-41-47(38,39)44-46(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1

InChI key

NLIGHACCLYZCOM-FHQWUTKFSA-M

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Application

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biochem/physiol Actions

Electron acceptor

Other Notes

Packaged based on NADP content as determined by UV-Vis.
This is the common form of NADP. Do not confuse with 3′-NADP or α-NADP.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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