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I9766

Sigma-Aldrich

D-myo-Inositol 1,4,5-tris-phosphate trisodium salt

≥95% (by 1H NMR and TLC)

Synonym(s):

Ins(1,4,5)P3

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About This Item

Empirical Formula (Hill Notation):
C6H12O15P3Na3
Molecular Weight:
486.04
PubChem Substance ID:
329815468
NACRES:
NA.25

Quality Level

300

Assay

≥95% (by 1H NMR and TLC)

form

powder

color

white

solubility

H2O: soluble

cation traces

K: <0.2%
Na: 12.5-16.0

storage temp.

−20°C

InChI

1S/C6H15O15P3.3Na/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;/q;3*+1/p-3/t1-,2+,3+,4-,5-,6-;;;/m1.../s1

InChI key

ZVCVTWVBDIPWPZ-ZKVWPJASSA-K

Biochem/physiol Actions

Stimulates intracellular calcium mobilization.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Precautionary Statements

P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Daniela M Arduino et al.
Molecular cell, 67(4), 711-723 (2017-08-19)
The mitochondrial calcium uniporter complex is essential for calcium (Ca2+) uptake into mitochondria of all mammalian tissues, where it regulates bioenergetics, cell death, and Ca2+ signal transduction. Despite its involvement in several human diseases, we currently lack pharmacological agents for
Hoa Thi Le et al.
Organic & biomolecular chemistry, 13(30), 8291-8297 (2015-07-04)
In order to detect small polyanions (sPAs), which play important roles in many biological systems, a triazolium cyclodextrin click cluster (5, hexakis{6-(3-methyl-4-hydroxymethyl-1H-1,2,3-triazolium-1-yl)-6-deoxy}-α-cyclodextrin iodide) was synthesized and characterized. The competition binding to 5 occupied by 5-carboxyfluorescein of inositol-1,4,5-trisphosphate (IP3), phytic acid

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