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H1252

Sigma-Aldrich

Homovanillic acid

Fluorimetric reagent

Synonym(s):

4-Hydroxy-3-methoxyphenylacetic acid, HVA

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About This Item

Linear Formula:
HOC6H3(OCH3)CH2CO2H
CAS Number:
Molecular Weight:
182.17
Beilstein:
2213447
EC Number:
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47

Quality Level

Assay

>99% (TLC)

form

powder

mp

142-145 °C (lit.)

solubility

ethanol: 50 mg/mL, colorless to light yellow

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

COc1cc(CC(O)=O)ccc1O

InChI

1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12)

InChI key

QRMZSPFSDQBLIX-UHFFFAOYSA-N

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Application

Homovanillic acid has been used as a standard in HPLC analysis.

Biochem/physiol Actions

Metabolite of dihydroxyphenylacetic acid (DOPAC) by catechol O-methyltransferase; reagent for the fluorimetric determination of glucose oxidase and other oxidative enzymes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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