Skip to Content
Merck
All Photos(1)

Documents

B4388

Sigma-Aldrich

2-Bromo-2-chloro-1,1,1-trifluoroethane

≥99%

Synonym(s):

Halothane

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
BrCH(Cl)CF3
CAS Number:
151-67-7
Molecular Weight:
197.38
Beilstein:
1736947
EC Number:
205-796-5
MDL number:
MFCD00009602
UNSPSC Code:
12352202
PubChem Substance ID:
24891772
NACRES:
NA.77

vapor pressure

4.5 psi ( 20 °C)

Quality Level

200

Assay

≥99%

form

liquid

contains

0.01% thymol as stabilizer

refractive index

n20/D 1.369 (lit.)

bp

50.2 °C (lit.)

density

1.872 g/mL at 25 °C (lit.)

SMILES string

FC(F)(F)C(Cl)Br

InChI

1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H

InChI key

BCQZXOMGPXTTIC-UHFFFAOYSA-N

Gene Information

human ... ATP5D(513) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GLRA1(2741) , GLRB(2743) , GRIA1(2890) , KCNK10(54207) , KCNK18(338567) , KCNK2(3776) , KCNK3(3777) , KCNK9(51305) , KCNN4(3783)

Looking for similar products? Visit Product Comparison Guide

Application

2-Bromo-2-chloro-1,1,1-trifluoroethane, or halothane, has been used in a study that combined molecular simulations with free energy simulations to study solvation of halothane in polarizable water and methanol. Halothane has also been used in a study to investigate the interaction of anesthetics with the Rho GTPase regulator Rho GDP dissociation inhibitor.

Biochem/physiol Actions

2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.

Signal Word

Danger

Hazard Statements

H315 - H318 - H335 - H360

Hazard Classifications

Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 1

1 of 1

Triethylamine trihydrofluoride 97%

Sigma-Aldrich

344648

Triethylamine trihydrofluoride

G I Elmer et al.
Behavioural brain research, 359, 950-957 (2018-06-23)
A growing body of clinical and preclinical research suggests that structural and functional changes in the habenula, a component of the epithalamus, are associated with major depressive disorder. A major excitatory, efferent projection from the habenula targets the rostromedial tegmentum
Mala Chakraborty et al.
Hepatology (Baltimore, Md.), 62(2), 546-557 (2015-02-26)
Clinical evidence suggests that many cases of serious idiosyncratic drug-induced liver injury are mediated by the adaptive immune system in response to hepatic drug-protein adducts, also referred to as "drug-induced allergic hepatitis"; but detailed mechanistic proof has remained elusive due
Samina Salim et al.
Behavioural brain research, 208(2), 545-552 (2010-01-13)
Recent work has suggested correlation of oxidative stress with anxiety-like behavior. There also is evidence for anxiolytic effects of physical exercise. However, a direct role of oxidative stress in anxiety is not clear and a protective role of physical exercise
Shinya Endo et al.
Toxicology, 319, 75-84 (2014-03-07)
MicroRNAs (miRNA) form a class of small non-coding RNA molecules that negatively regulate gene expression. Most cellular pathways are modulated by miRNAs. However, the pathophysiological role of miRNAs during drug-induced liver injury (DILI) remains largely unknown. In this study, the
Travis J A Craddock et al.
PloS one, 7(6), e37251-e37251 (2012-07-05)
The cytoskeleton is essential to cell morphology, cargo trafficking, and cell division. As the neuronal cytoskeleton is extremely complex, it is no wonder that a startling number of neurodegenerative disorders (including but not limited to Alzheimer's disease, Parkinson's disease and
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service