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A9187

Sigma-Aldrich

Adenosine 5′-triphosphate magnesium salt

≥95%, bacterial

Synonym(s):

ATP, ATP magnesium salt

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About This Item

Empirical Formula (Hill Notation):
C10H16N5O13P3 · xMg2+
CAS Number:
74804-12-9
Molecular Weight:
507.18 (free acid basis)
MDL number:
MFCD00084767
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
24891422
NACRES:
NA.51

biological source

bacterial

Quality Level

200

Assay

≥95%

form

powder

solubility

H2O: 50 mg/mL

storage temp.

−20°C

SMILES string

[Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H16N5O13P3.Mg.2H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;

InChI key

CPGAIACWYFBIFN-UHFFFAOYSA-N

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Application

Adenosine 5′-triphosphate magnesium salt has been used:
  • as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
  • as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
  • as a component in action potential intracellular solution

Biochem/physiol Actions

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Pictograms

Health hazard
GHS08

Signal Word

Warning

Hazard Statements

H371

Hazard Classifications

STOT SE 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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