Skip to Content
Merck
All Photos(1)

Documents

Y0001422

Valproic acid for system suitability

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-Propylpentanoic acid, Valproic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(CH3CH2CH2)2CHCO2H
CAS Number:
99-66-1
Molecular Weight:
144.21
MDL number:
MFCD00002672
UNSPSC Code:
41116107
PubChem Substance ID:
329831418
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

valproic acid

manufacturer/tradename

EDQM

refractive index

n20/D 1.425 (lit.)

bp

220 °C (lit.)

density

0.9 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCC(C(O)=O)CCC

InChI

1S/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)

InChI key

NIJJYAXOARWZEE-UHFFFAOYSA-N

Gene Information

human ... ALDH5A1(7915)

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Valproic acid for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Signal Word

Danger

Hazard Statements

H302,H315,H318,H360FD

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1A - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Valproic Acid, Sodium Salt A cell-permeable, short-chained fatty acid that inhibits histone deacetylase (IC₅₀ = 400 µM for HDAC1).

Sigma-Aldrich

676380

Valproic Acid, Sodium Salt

Sodium valproate European Pharmacopoeia (EP) Reference Standard

S0930000

Sodium valproate

Trichostatin A, Ready Made Solution 5 mM in DMSO, from Streptomyces sp.

Sigma-Aldrich

T1952

Trichostatin A, Ready Made Solution

Anton Pohanka et al.
Scandinavian journal of clinical and laboratory investigation, 74(7), 648-652 (2014-07-26)
Therapeutic drug monitoring (TDM) of the antiepileptic drug valproic acid (VPA) is recommended in patients with multiple drug therapy or with concomitant disabilities to ensure treatment efficacy and avoid adverse reactions in both adults and children. The use of sampling
Hubert Arokium et al.
PloS one, 9(10), e108682-e108682 (2014-10-08)
Long interspersed element-1 (LINE-1 or L1) retrotransposition induces insertional mutations that can result in diseases. It was recently shown that the copy number of L1 and other retroelements is stable in induced pluripotent stem cells (iPSCs). However, by using an
Alexa P Vitins et al.
Archives of toxicology, 88(8), 1573-1588 (2014-02-19)
Liver injury is the leading cause of drug-induced toxicity. For the evaluation of a chemical compound to induce toxicity, in this case steatosis or fatty liver, it is imperative to identify markers reflective of mechanisms and processes induced upon exposure
Zhida Liu et al.
Scientific reports, 4, 7266-7266 (2014-12-02)
In the history of vaccine development, the synthetic vaccine is a milestone that is in stark contrast with traditional vaccines based on live-attenuated or inactivated microorganisms. Synthetic vaccines not only are safer than attenuated or inactivated microorganisms but also provide
Jennifer A Corcoran et al.
PLoS pathogens, 11(1), e1004597-e1004597 (2015-01-09)
Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious cause of several AIDS-related cancers, including the endothelial cell (EC) neoplasm Kaposi's sarcoma (KS). KSHV-infected ECs secrete abundant host-derived pro-inflammatory molecules and angiogenic factors that contribute to tumorigenesis. The precise contributions of viral
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service