Skip to Content
Merck
All Photos(1)

Documents

PHL82542

Fisetin

phyproof® Reference Substance

Synonym(s):

3,3′,4′,7-Tetrahydroxyflavone, 5-Desoxyquercetin, Cotinin, Fiestin, Fietin

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
Molecular Weight:
286.24
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

Assay

≥90.0% (HPLC)

manufacturer/tradename

PhytoLab

application(s)

food and beverages

format

neat

InChI

1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

InChI key

XHEFDIBZLJXQHF-UHFFFAOYSA-N

Related Categories

General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application

  • Fisetin anti-inflammatory and antioxidative properties: Fisetin reduces inflammation and oxidative stress in deep vein thrombosis, signaling via the MAPK and NRF2 pathways, highlighting its potential as an anti-inflammatory agent and its importance in managing thrombotic disorders (Liu and Lu, 2024).
  • Fisetin in drug delivery system enhancement: A mechanochemical method improves fisetin′s solubility and biological activity, suggesting its utility in creating effective drug delivery systems that enhance the therapeutic effects of fisetin, particularly relevant in flavonoid research for increased bioavailability (Rosiak et al., 2024).
  • Fisetin combination therapy for neuropathic pain: Utilizing fisetin with other treatments like pregabalin and gabapentin shows effectiveness in managing neuropathic pain, demonstrating fisetin′s role in enhancing pain management therapies and its potential in neuropharmacology (Karabacak et al., 2024).
  • Fisetin in neurodegenerative disease research: Fisetin interacts with gut microbiota to offer a novel therapeutic approach in preventing and treating neurodegenerative diseases like Parkinson′s, underscoring its role in neuroprotective dietary interventions and the development of nutraceuticals (Yao et al., 2024).
  • Fisetin in cardiovascular disease management: Fisetin suppresses atherosclerosis in apolipoprotein E knockout mice by inhibiting ferroptosis-related oxidative stress, indicating its potential use as a therapeutic agent in cardiovascular disease through modulation of oxidative stress pathways (Jiang et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Quercetin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1488

Quercetin

Chrysin ≥96.5%

Sigma-Aldrich

C80105

Chrysin

4-Hydroxybenzhydrazide ≥97%

Sigma-Aldrich

H9882

4-Hydroxybenzhydrazide

Silibinin ≥98% (HPLC)

Sigma-Aldrich

S0417

Silibinin

Luteolin ≥98% (TLC), powder

Sigma-Aldrich

L9283

Luteolin

Resveratrol ≥99% (HPLC)

Sigma-Aldrich

R5010

Resveratrol

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service