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C2300000

Clofibrate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

2-(4-Chlorophenoxy)-2-methylpropionic acid ethyl ester, Ethyl 2-(4-chlorophenoxy)-2-methylpropionate, Ethyl 2-(4-chlorophenoxy)isobutyrate

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About This Item

Empirical Formula (Hill Notation):
C12H15ClO3
CAS Number:
637-07-0
Molecular Weight:
242.70
Beilstein:
1913459
MDL number:
MFCD00000615
UNSPSC Code:
41116107
PubChem Substance ID:
329774991
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

clofibrate

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1

InChI

1S/C12H15ClO3/c1-4-15-11(14)12(2,3)16-10-7-5-9(13)6-8-10/h5-8H,4H2,1-3H3

InChI key

KNHUKKLJHYUCFP-UHFFFAOYSA-N

Gene Information

human ... PPARA(5465)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Clofibrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Product No.
Description
Pricing

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

closed cup

Flash Point(C)

closed cup

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Hypolipidemic effect of clofibrate and fatty acid oxidation in peroxisomes.
Nutrition reviews, 35(4), 74-75 (1977-04-01)
[The treatment of essential hyperlipidemia with clofibrate].
W Reuter et al.
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 24(1), Suppl:184-Suppl:187 (1969-01-01)
[Currently used therapeutic agents for arteriosclerosis--with special reference ro a protein anabolic hormone, clofibrate (C.P.I.B.)].
T Yasugi et al.
Nihon rinsho. Japanese journal of clinical medicine, 28(5), 1470-1474 (1970-05-01)
[Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].
L M Dobordzhginidze et al.
Kardiologiia, 44(2), 96-103 (2004-05-06)
Clofibrate.
IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, 24, 39-58 (1980-01-01)
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