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BP670

Norfloxacin

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid, 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-3-quinolinecarboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C16H18FN3O3
CAS Number:
70458-96-7
Molecular Weight:
319.33
EC Number:
274-614-4
MDL number:
MFCD00079532
UNSPSC Code:
12352200

grade

pharmaceutical primary standard

API family

norfloxacin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical

format

neat

SMILES string

CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3

InChI

1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)

InChI key

OGJPXUAPXNRGGI-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Norfloxacin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Norfloxacin Tablets

    • Biochem/physiol Actions

    Norfloxacin blocks DNA replication by interfering with an ATP-induced structural transition of DNA complexed with DNA gyrase (topoisomerase).
    Mode of action: inhibits bacterial DNA replication
    Antimicrobial spectrum: Gram-negative bacteria; less effective against Gram-positive bacteria

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    Norfloxacin for peak identification, European Pharmacopoeia (EP) Reference Standard

    1471506

    Norfloxacin, United States Pharmacopeia (USP) Reference Standard

    1471517

    Norfloxacin Related Compound A, United States Pharmacopeia (USP) Reference Standard

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    1471583

    Norfloxacin Related Compound H, United States Pharmacopeia (USP) Reference Standard

    1471619

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    PHR1614

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    Pictograms

    Exclamation mark
    GHS07

    Signal Word

    Warning

    Hazard Statements

    H319

    Hazard Classifications

    Eye Irrit. 2

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 2

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    Certificates of Analysis (COA)

    Lot/Batch Number

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