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BP459

Riboflavin sodium phosphate

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Riboflavin 5′-monophosphate sodium salt, Riboflavin Sodium phosphate

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About This Item

Empirical Formula (Hill Notation):
C17H20N4NaO9P
CAS Number:
130-40-5
Molecular Weight:
478.33
Beilstein:
4106529
EC Number:
204-988-6
MDL number:
MFCD00065362
UNSPSC Code:
41106305
NACRES:
NA.24

grade

pharmaceutical primary standard

Agency

BP

API family

riboflavin

form

solid

quality

British Pharmacopoeia (BP) Reference Standard

manufacturer/tradename

BP

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

mp

240-245 °C

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O)c2cc1C

InChI

1S/C17H21N4O9P.Na/c1-7-3-9-10(4-8(7)2)21(15-13(18-9)16(25)20-17(26)19-15)5-11(22)14(24)12(23)6-30-31(27,28)29;/h3-4,11-12,14,22-24H,5-6H2,1-2H3,(H,20,25,26)(H2,27,28,29);/q;+1/p-1/t11-,12+,14-;/m0./s1

InChI key

OHSHFZJLPYLRIP-BMZHGHOISA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Riboflavin sodium phosphate is a supplement form of riboflavin (vitamin B2), which is necessary for human nutrition, and growth. It finds potential applications in biological redox reactions and is found in several foodstuffs, energy drinks, and vitamin formulations.

Application

Riboflavin sodium phosphate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Vitamins B and C Injection

    • Packaging

    Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

    Storage Class Code

    11 - Combustible Solids

    WGK

    WGK 1

    Flash Point(F)

    Not applicable

    Flash Point(C)

    Not applicable

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    USP

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    Sigma-Aldrich

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    Sigma-Aldrich

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    Riboflavin sodium phosphate
    European Pharmacopoeia Commission and European Directorate for the Quality of Medicines & Healthcare
    European pharmacopoeia, 5(2), 3485-3487 (2017)
    The simultaneous assay of riboflavin 5-phosphate sodium and other water-soluble vitamins in liquid multivitamin formulations by liquid chromatograph
    Lam FL and Lowande A
    Journal of Pharmaceutical and Biomedical Analysis, 6(1), 87-95 (1988)
    Differential pulse polarographic method development and validation of riboflavin in pharmaceutical formulation
    Kashid LM and Patil SV
    International Journal of Scientific Research, 5(2), 325-334 (2015)
    Simultaneous determination of riboflavin phosphate and other ingredients in a multivitamin pharmaceutical preparation by on-line automated LC coupled with pre-column immobilized enzyme reactor
    Ono M, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 29(1-2), 325-334 (2002)

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