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Supelco

Leucomalachite Green

analytical standard

Synonym(s):

4,4′-Benzylidenebis(N,N-dimethylaniline)

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About This Item

Linear Formula:
C6H5CH[C6H4N(CH3)2]2
CAS Number:
129-73-7
Molecular Weight:
330.47
Beilstein:
2140506
EC Number:
204-961-9
MDL number:
MFCD00008315
UNSPSC Code:
85151701
PubChem Substance ID:
329761851
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

100-102 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

SMILES string

CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C

InChI

1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3

InChI key

WZKXBGJNNCGHIC-UHFFFAOYSA-N

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General description

Leucomalachite green is a triphenylmethane dye and a metabolite of malachite green.

Application

Leucomalachite green may be used as an analytical reference standard for the quantification of the analyte in fish samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Signal Word

Warning

Hazard Statements

H302,H341,H351,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number

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A simple and rapid method for the identification and quantification of malachite green and its metabolite in hake by HPLC?MS/MS
Nebot C, et al.
Food Control, 31(1), 102-107 (2013)
Determination of malachite green and leucomalachite green in edible goldfish muscle by liquid chromatography?ion trap mass spectrometry
Lee C-K, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 843(2), 247-251 (2006)
Chaoyang Long et al.
Journal of chromatography. A, 1203(1), 21-26 (2008-07-29)
With a new oxidant for post-column chemical derivation, a novel approach was developed for the determination of Malachite Green (MG) and Leucomalachite Green (LMG) in fish by high-performance liquid chromatography (HPLC). A C(8) column was used for separation, and elution
Zoe Hall et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 874(1-2), 95-100 (2008-09-27)
A high accuracy method for the quantification of malachite green (MG) and leucomalachite green (LMG) in salmon is described. Analytical challenges including the effects of analyte instability and matrix suppression were minimised by the use of exact matching isotope dilution
Andrew Renwick et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48 Suppl 1, S75-S80 (2009-09-30)
Leucomalachite green (LMG) is mutagenic and produces DNA-adducts in vivo, and is carcinogenic in rodent bioassays. Dose-response modelling of the data for hepatocellular adenomas and carcinomas in female mice gave a BMDL10 of 20 mg/kg-bw/day. Limited data are available on
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