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386464

Sigma-Aldrich

Diisopropylamine

purified by redistillation, 99.95%

Synonym(s):

DIPA

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About This Item

Linear Formula:
(CH3)2CHNHCH(CH3)2
CAS Number:
Molecular Weight:
101.19
Beilstein:
605284
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

3.5 (vs air)

Quality Level

vapor pressure

50 mmHg ( 20 °C)

Assay

99.95%

form

liquid

autoignition temp.

599 °F

purified by

redistillation

expl. lim.

8.5 %

refractive index

n20/D 1.392 (lit.)

bp

84 °C (lit.)

mp

−61 °C (lit.)

solubility

water: soluble 110 g/L at 25 °C

density

0.722 g/mL at 25 °C (lit.)

SMILES string

CC(C)NC(C)C

InChI

1S/C6H15N/c1-5(2)7-6(3)4/h5-7H,1-4H3

InChI key

UAOMVDZJSHZZME-UHFFFAOYSA-N

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General description

Diisopropylamine (DIPA) is an aliphatic secondary amine widely used as an organic base in organic synthesis. Its standard molar enthalpy of formation and combustion has been measured.

Application

Diisopropylamine may be used in the following processes:
  • Synthesis of diisopropylamine methyl urea (DMU).
  • Synthesis of N,N-diisopropyl quinoline-2-carboxamide.
  • Synthesis of 3-N-sulfonylamidine coumarins.
  • Synthesis of N-chloroamine, an intermediate to generate amides.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

7.8 °F - closed cup

Flash Point(C)

-13.45 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Research on Synthesis and Corrosion Inhibitory Performance of Diisopropylamine Methyl Urea.
Zhou FR and Zhang H.
Applied Mechanics and Materials, 713, 2839-2842 (2015)
Iron-Catalyzed Direct Synthesis of Amides from Methylarenes.
Kotha SS, et al.
Advanced Synthesis & Catalysis, 357(7), 1437-1445 (2015)
Microwave-Assisted Copper-Catalyzed Four Component Tandem Synthesis of 3-N-Sulfonylamidine Coumarins.
Murugavel G and Punniyamurthy T.
The Journal of Organic Chemistry, 80 (12), 6291-6299 (2015)
A simple and novel amide ligand based on quinoline derivative used for palladium-catalyzed Suzuki coupling reaction.
Liu H, et al.
Journal of Organometallic Chemistry, 794, 27-32 (2015)
Enthalpies of combustion of di-n-propylamine, diisopropylamine, diisobutylamine, and di-sec-butylamine.
Ribeiro da Silva MAV, et al.
The Journal of Chemical Thermodynamics, 29(9), 1025-1030 (1997)

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