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18309

Supelco

Ginkgolide C

analytical standard

Synonym(s):

1,7-Dihydroxy-ginkgolide A

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About This Item

Empirical Formula (Hill Notation):
C20H24O11
CAS Number:
15291-76-6
Molecular Weight:
440.40
MDL number:
MFCD02094178
UNSPSC Code:
85151701
PubChem Substance ID:
329751661
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥96.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

−20°C

SMILES string

[H][C@@]12OC(=O)[C@@H](C)[C@]1(O)[C@@]34OC5OC(=O)[C@H](O)C56[C@@H]([C@H](O)[C@@H](OC3=O)[C@@]46[C@H]2O)C(C)(C)C

InChI

1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6+,7+,8+,9+,10-,11+,15?,17?,18-,19-,20-/m1/s1

InChI key

AMOGMTLMADGEOQ-CFTQXCTRSA-N

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General description

Ginkgolide C is an active constituent of Ginkgo biloba. The ginkgo leaves has several pharmacological properties, some of them being; improved blood flow, radical scavenging, vasoprotection, and anti-PAF (platelet aggregating factor) activity. Ginkgolide C along with the other active constituents of Ginkgo biloba, is responsible for the inhibition of PAF activity.

Application

It may be used as a reference standard in determination of ginkgolide from Ginkgo biloba commercial product, using HPLC with evaporative light-scattering detection.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This compound is commonly found in plants of the genus: ginkgo

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF1867
BCCC8870
BCCC8869
BCCC3729
BCCB7016

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Rapid determination of terpene lactones in Ginkgo Biloba commercial products by HPLC with evaporative light-scattering detection.
Herring, Tim.
LCGC North America, 22.5, 456-462 (2004)
Quantitative analysis of bilobalide and ginkgolides from Ginkgo biloba leaves and Ginkgo products using (1)H-NMR.
Choi YH
Chemical & Pharmaceutical Bulletin, 51(2), 158-161 (2003)
Haixia Lin et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 338-349 (2014-03-07)
Ginkgo biloba has been used for many thousand years as a traditional herbal remedy and its extract has been consumed for many decades as a dietary supplement. Ginkgo biloba leaf extract is a complex mixture with many constituents, including flavonol

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