16866
Monoethylglycinexylidine
analytical standard
Synonym(s):
MEGX, MGEX, Monoethylglycinexylidide, N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide, Norlidocaine
About This Item
Recommended Products
grade
analytical standard
Quality Level
Assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical
format
neat
SMILES string
CC1=C(NC(CNCC)=O)C(C)=CC=C1
InChI
1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)
InChI key
WRMRXPASUROZGT-UHFFFAOYSA-N
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Related Categories
Application
- Pharmacokinetic Analysis: A study by Liu ZY et al. examines the pharmacokinetics of intravenous and topical lidocaine in patients undergoing thoracoscopic pulmonary resection. This research, which could integrate compounds like Monoethylglycinexylidine for analytical validation, highlights the importance of understanding drug dynamics for improving surgical outcomes (Liu et al., 2024).
- Veterinary Pharmacology: Knych HK et al. explore the pharmacokinetics and metabolism of lidocaine in horses following a palmar digital nerve block. Studies like this could benefit from the use of Monoethylglycinexylidine as a standard for accurate drug measurement and monitoring in veterinary medicine, ensuring safe and effective dosing (Knych et al., 2023).
- Anesthesia Research: Crouch CE et al. provide insights into the pharmacokinetics of lidocaine intraoperative infusion during partial hepatectomy for living liver donation. Research utilizing Monoethylglycinexylidine could enhance the understanding of local anesthetics′ systemic effects, contributing to safer anesthetic practices (Crouch et al., 2023).
- Anesthetic Efficacy in Avian Species: Escobar A et al. investigate the effects of two continuous infusion doses of lidocaine on isoflurane minimum anesthetic concentration in chickens. Incorporating Monoethylglycinexylidine in such studies could refine our understanding of dose-dependent effects and optimize anesthetic protocols for non-mammalian species (Escobar et al., 2023).
- Clinical Pharmacokinetics: Jin Y et al. discuss the simultaneous determination of lidocaine and its active metabolites in plasma by UPLC-MS/MS, applied to a clinical pharmacokinetic study in liver cancer patients. Monoethylglycinexylidine could be used to validate and calibrate assays, enhancing the reliability of pharmacokinetic data in clinical settings (Jin et al., 2022).
Biochem/physiol Actions
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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