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MC0HC10FS1

Millipore

Millistak+® HC Pod Depth Filter

C0HC, cellulose, filtration area 1.1 m2, hydrophilic

Synonym(s):

Millistak+ HC Pod Depth Filter, C0HC media series, 1.1 m 2 surface area

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About This Item

UNSPSC Code:
23151806
eCl@ss:
32031690

material

cellulose
filter aid (inorganic)
glass fiber-reinforced polypropylene

Quality Level

400

description

Perfusion bioreactor fluid

feature

hydrophilic

manufacturer/tradename

Millistak+®

parameter

1 bar max. differential pressure (15 psid) at 80 °C (Forward)
1 bar max. inlet pressure (15 psi) at 80 °C
2.1 bar max. differential pressure (30 psid) at 25 °C (Forward)
2.1 bar max. differential pressure (30 psid) at 25 °C (Reverse)
3.5 bar max. inlet pressure (50 psi) at 25 °C

H

32 cm (12.5 in.)

L

62 cm (24.2 in.)

filtration area

1.1 m2

impurities

<0.25 EU/mL bacterial endotoxins (LAL test, Aqueous extraction)

gravimetric extractables

39-69 mg/m2

total organic carbon (TOC) residue

720-1260 ppb

input

sample type liquid

conductivity

8.66-10.5 μS/cm at 25 °C (product water)

filter grade

C0HC

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General description

The Millistak+® depth filter media is offered in a scalable, disposable format providing greater flexibility because of its unique modular design. The Millistak+® MC0HC10FS1 comes in a High Capacity POD format featuring a 32 cm (H) x 62 cm (L) and a filtration area of 1.1 m2.

This C0HC media series delivers optimal performance through a gradient density matri, ideal for primary clarification applications. Millistak+® Pod filters are available in three distinct series of media grades in order to meet your specific needs - DE, CE and HC.

The Millistak+® Pod system is ideal for a wide variety of primary and secondary clarification applications, including cell cultures, yeast and E. coli lysates post centrifuge, E. coli refolds, media, vaccines, plasma proteins and sera.

Easy to Use

With the compact, modular design of our Millistak+® new Pod system, you can increase productivity and shorten cycle times.

Installation and setup of the Pod system is simple and straightforward. The unique design of the disposable adapters and disposable manifolds makes it easy to connect the Pod filters to rest of the unit operations in the process. The self-contained and disposable nature of the system protects operators from exposure to biohazards and eliminates maintenance as well as cleaning validation requirements.

Application

Perfusion bioreactor fluid

Features and Benefits

  • Low hold-up volume for greater product yield
  • Broad range of media types offered in single and multilayer products
  • Millistak+® HC dual-action media improves prefiltration and compresses clarification
  • Flexible, modular format offers scalability from 5 to 12,000 liters or more
  • Patented disposable design eliminates need for housing, CIP or cleaning validation
  • Self-contained Pod filters protect operators from exposure to biohazards
  • Robust construction is easy to use and set up
  • Smaller footprint facilitates use in tight spaces

Specifications

Filter Grade: C0HC
Per 24 hour soak in 10 L pure water post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 100 L/m2 (10 L/ft2) of media surface area:
Sodium: <3.0 mg/ft2
Calcium: <0.7 mg/ft2
Magnesium: <0.2 mg/ft2
Mercury: <0.01 mg/ft2
Chromium: <0.01 mg/ft2
Aluminum: <0.01 mg/ft2
Potassium: <0.01 mg/ft2
Lead: <0.01 mg/ft2
Arsenic: <0.01 mg/ft2
Cobalt: <0.01 mg/ft2
Iron: <0.01 mg/ft2
Manganese: <0.01 mg/ft2
Titanium: <0.01 mg/ft2
Zinc: <0.01 mg/ft2

Preparation Note

Sterilization Method
1 autoclave cycle of 60 min @ 123 °C

Analysis Note

Gravimetric Extractables: After 24 hour static soak in pure water (Type 1 DI Water) post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 100 L/m2 of media surface area
Product Water Conductivity at 25°C: post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 10 liters per ft2 (100 L/m2) of media surface area
Total Organic Carbon (TOC) Residue: post autoclave (1 cycle of 60 minutes at 123 °C) and pure water flush of 100 L/m2 of media surface area

Legal Information

MILLISTAK+ is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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