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8.53018

Sigma-Aldrich

Boc-Lys(2-Cl-Z)-OH

(cryst) Novabiochem®

Synonym(s):

Boc-Lys(2-Cl-Z)-OH, N-α-t.-Boc-N-ε-2-chloro-CBZ-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C19H27ClN2O6
CAS Number:
Molecular Weight:
414.88
UNSPSC Code:
12352209
NACRES:
NA.22

Quality Level

product line

Novabiochem®

Assay

≥95.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

70-73 °C

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

InChI

1S/C19H27ClN2O6/c1-19(2,3)28-18(26)22-15(16(23)24)10-6-7-11-21-17(25)27-12-13-8-4-5-9-14(13)20/h4-5,8-9,15H,6-7,10-12H2,1-3H3,(H,21,25)(H,22,26)(H,23,24)

InChI key

ATUMDPHEFWGCJF-UHFFFAOYSA-N

General description

Standard building block for introduction of lysine amino-acid residues by Boc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

[1] K. Noda, et al. (1969) Bull. Chem. Soc. Jpn., 43, 1883.
[2] B. W. Erickson, et al. (1973) J. Am. Chem. Soc., 95, 3757.

Linkage

Replaces: 04-12-0068

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -12.0 - -10.0 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Solubility (1mmoll in 2ml DCM): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Enantiomeric purity: ≥ 99.5 % (a/a)

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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