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8.52039

Sigma-Aldrich

Fmoc-Thi-OH

Novabiochem®

Synonym(s):

Fmoc-Thi-OH, N-α-Fmoc-β-thienyl-L-alanine

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About This Item

Empirical Formula (Hill Notation):
C22H19NO4S
CAS Number:
Molecular Weight:
393.46
MDL number:
UNSPSC Code:
12352209

Quality Level

product line

Novabiochem®

Assay

≥96.0% (acidimetric)
≥98% (TLC)
≥99.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

170-180 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

InChI

1S/C22H19NO4S/c24-21(25)20(12-14-6-5-11-28-14)23-22(26)27-13-19-17-9-3-1-7-15(17)16-8-2-4-10-18(16)19/h1-11,19-20H,12-13H2,(H,23,26)(H,24,25)/p-1/t20-/m0/s1

InChI key

PXBMQFMUHRNKTG-FQEVSTJZSA-M

General description

Standard building block for introduction of thienylalanine by Fmoc SPPS. Useful replacement for Phe.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Linkage

Replaces: 04-12-1082

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(157B)): ≥ 98 %
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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