Skip to Content
Merck
All Photos(1)

Documents

8.07491

Sigma-Aldrich

Polyethylene glycol

6000, for synthesis

Synonym(s):

Poly(ethylene glycol), Polyethylene glycol 6000, Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 6000, PEG

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
MDL number:
UNSPSC Code:
13111021
EC Index Number:
500-038-2

vapor pressure

<0.01 hPa ( 20 °C)

Quality Level

form

solid

autoignition temp.

420 °C

potency

28000 mg/kg LD50, oral (Rat)
>20000 mg/kg LD50, skin (Rabbit)

pH

5-7 (20 °C, 100 g/L in H2O)

mp

58-63 °C

transition temp

flash point 270 °C

density

1.2 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Polyethylene glycol (PEG) is a synthetic, hydrophilic, biocompatible polymer that has a wide range of uses in PEGylation, surface conjugation, nanoparticle coating, and crosslinking for hydrogels, etc. PEGs are made by polymerizing ethylene oxide via a ring-opening reaction to produce a wide range of molecular weights and molecular weight distributions (polydispersity).

Application

Polyethylene glycol 6000 is a non-ionic surfactant that can be used as a structure-directing agent to prepare mesoporous γ-Al2O3. PEG 6000 induced the formation of the lamellate structure morphology of boehmite nanoparticles with improved textural properties such as high surface area, larger pore volume, and pore size. It is also used in drug formulations to enhance the dissolution rate of the poorly water-soluble drug molecule. PEG-6000 can also be used in the purification of nucleic acids via the selective precipitation method. This approach is economically cost-effective and faster than the commonly employed chromatographic purification method.

Analysis Note

Melting range (lower value): ≥ 59 °C
Melting range (upper value): ≤ 64 °C
Hydroxyl value: 16 - 23
Average molecular mass: 5000 - 7000
Identity (IR): passes test

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

281.5 °F - closed cup

Flash Point(C)

138.6 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 6

1 of 6

Polyethylene glycol 8000 United States Pharmacopeia (USP) Reference Standard

USP

1546605

Polyethylene glycol 8000

Polyethylene glycol 400, for synthesis

Sigma-Aldrich

8.07485

Polyethylene glycol

Polyethylene glycol 600, for synthesis

Sigma-Aldrich

8.07486

Polyethylene glycol

Polyethylene glycol 1000, for synthesis

Sigma-Aldrich

8.07488

Polyethylene glycol

Polyethylene glycol 10000, for synthesis

Sigma-Aldrich

8.21881

Polyethylene glycol

Polyethylene glycol 3000, for synthesis

Sigma-Aldrich

8.19015

Polyethylene glycol

S Biswal et al.
AAPS PharmSciTech, 9(2), 563-570 (2008-05-07)
The aim of the present study was to enhance the dissolution rate of gliclazide using its solid dispersions (SDs) with polyethylene glycol (PEG) 6000. The phase solubility behavior of gliclazide in presence of various concentrations of PEG 6000 in 0.1

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service