860501P
Avanti
C22 Ceramide (d18:1/22:0)
Avanti Polar Lipids 860501P, powder
Synonym(s):
N-behenoyl-D-erythro-sphingosine
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C40H79NO3
CAS Number:
Molecular Weight:
622.06
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 10 mg (860501P-10mg)
pkg of 1 × 5 mg (860501P-5mg)
manufacturer/tradename
Avanti Polar Lipids 860501P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
General description
C22 Ceramide (d18:1/22:0) or N-behenoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with behenic acid.
Application
C22 Ceramide (d18:1/22:0) has been used:
- as a standard to measure ceramide concentrations in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (LC/MS2)
- as a standard for the quantitation of sphingolipid metabolites
- to study its effects on mitochondrial-to-cytosolic stress response (MCSR) induction
Biochem/physiol Actions
Ceramides plays an important role in regulating cell differentiation, proliferation and apoptosis. It also regulates stress responses and inflammation.
Packaging
5 mL Amber Glass Screw Cap Vial (860501P-10mg)
5 mL Amber Glass Screw Cap Vial (860501P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
Hyun-Eui Kim et al.
Cell, 166(6), 1539-1552 (2016-09-10)
Defects in mitochondrial metabolism have been increasingly linked with age-onset protein-misfolding diseases such as Alzheimer's, Parkinson's, and Huntington's. In response to protein-folding stress, compartment-specific unfolded protein responses (UPRs) within the ER, mitochondria, and cytosol work in parallel to ensure cellular
Donato A Rivas et al.
Journal of applied physiology (Bethesda, Md. : 1985), 113(11), 1727-1736 (2012-10-09)
One of the most fundamental adaptive physiological events is the response of skeletal muscle to high-intensity resistance exercise, resulting in increased protein synthesis and ultimately larger muscle mass. However, muscle growth in response to contraction is attenuated in older humans.
Ebru Afşar et al.
Redox biology, 30, 101430-101430 (2020-01-25)
We aimed to determine sphingolipid levels and examine apoptotic pathways in human retinal pigment epithelial cells (ARPE-19) undergoing endoplasmic reticulum (ER) stress. Cells were treated with tunicamycin (TM) to induce ER stress and tauroursodeoxycholic acid (TUDCA), an ER stress inhibitor
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service