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860398P

Avanti

18:0-d35 Lyso PC

Avanti Polar Lipids 860398P, powder

Synonym(s):

1-stearoyl-d35-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C26H19NO7PD35
CAS Number:
327178-92-7
Molecular Weight:
558.90
UNSPSC Code:
12352100
NACRES:
NA.25

Assay

>99% (LPC; may contain up to 10% of the 2-LPC isomer, TLC)

form

powder

packaging

pkg of 1 × 10 mg (860398P-10mg)

manufacturer/tradename

Avanti Polar Lipids 860398P

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2

General description

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.
Lysophosphatidylcholine (Lyso PC) is a bioactive proinflammatory phospholipid and a component of oxidized low-density lipoprotein (Ox-LDL). It is produced during various pathological activities.

Biochem/physiol Actions

Lysophosphatidylcholine (Lyso PC) on acylation by yeast protein Ypr140w yields phosphatidylcholine (PC). Lyso PC alters functions in a numerous cell-types, such as endothelial cells, smooth muscle cells, monocytes, macrophages, and T-cells and leads to the development of atherosclerosis and inflammatory diseases.

Packaging

5 mL Amber Glass Screw Cap Vial (860398P-10mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Role of Lysophosphatidylcholine (LPC) in Atherosclerosis
Takayuki M, et al.
Current Medicinal Chemistry, 14, 3209-3220 (2007)
Ypr140wp,?the yeast tafazzin', displays a mitochondrial lysophosphatidylcholine (lyso-PC) acyltransferase activity related to triacylglycerol and mitochondrial lipid synthesis
Testet E, et al.
The Biochemical Journal, 387 (2005)

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