Skip to Content
Merck
All Photos(2)

Documents

840037P

Avanti

16:0 PS

Avanti Polar Lipids

Synonym(s):

1,2-dihexadecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DPPS; PS(16:0/16:0); 110668

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C38H73NO10PNa
CAS Number:
145849-32-7
Molecular Weight:
757.95
UNSPSC Code:
51191904
NACRES:
NA.25

description

1,2-dipalmitoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 10 mg (840037P-10mg)
pkg of 1 × 200 mg (840037P-200mg)
pkg of 1 × 25 mg (840037P-25mg)
pkg of 1 × 500 mg (840037P-500mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C38H74NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-36(40)46-31-34(32-47-50(44,45)48-33-35(39)38(42)43)49-37(41)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;/h34-35H,3-33,39H2,1-2H3,(H,42,43)(H,44,45);/q;+1/p-1/t34-,35+;/m1./s1

InChI key

GTLXLANTBWYXGW-CEGNZRHUSA-M

General description

Phosphatidylserine (PtdSer) is an anionic phospholipid abundantly present in the eukaryotic cell. 10% of the total cellular lipid consists of phosphatidylserine. O‐phospho‐L‐serine is a heat‐stable substrate.

Application

16:0 PS has been used in the assay to measure interactions between purified dynamin-related protein 1 (Drp1) and synthetic liposomes.
16:0 PS may be used in liposome flotation assay to measure its interactions between purified dynamin related protein 1 (Drp1) and as a component in the lipid mixtures to prepare lipid monolayers. It has also been used to prepare liposomes by the lipid film hydration method.

Biochem/physiol Actions

Phosphatidylserine (PtdSer) participates in various intracellular signaling pathways. It also play a major role in apoptosis and blood clotting.

Packaging

20 mL Clear Glass Screw Cap Vial (840037P-200mg)
30 mL Amber Wide Mouth Bottle with Screw Cap (840037P-500mg)
5 mL Amber Glass Screw Cap Vial (840037P-10mg)
5 mL Amber Glass Screw Cap Vial (840037P-25mg)

also commonly purchased with this product

Product No.
Description
Pricing

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 8

1 of 8

18:1 BMP (S,S) sn-(3-oleoyl-2-hydroxy)-glycerol-1-phospho-sn-1′-(3′-oleoyl-2′-hydroxy)-glycerol (ammonium salt), powder

Avanti

857135P

18:1 BMP (S,S)

18:2 (Cis) PC (DLPC) 1,2-dilinoleoyl-sn-glycero-3-phosphocholine, chloroform

Avanti

850385C

18:2 (Cis) PC (DLPC)

16:0 PG Avanti Polar Lipids

Avanti

840455P

16:0 PG

18:2 (Cis) PC (DLPC) Avanti Polar Lipids

Avanti

850385P

18:2 (Cis) PC (DLPC)

18:1 PS (DOPS) Avanti Polar Lipids

Avanti

840035C

18:1 PS (DOPS)

16:0 PC (DPPC) Avanti Polar Lipids

Avanti

850355C

16:0 PC (DPPC)

Cholesterol (ovine) Avanti Polar Lipids

Avanti

700000P

Cholesterol (ovine)

18:1 Cardiolipin Avanti Polar Lipids

Avanti

710335P

18:1 Cardiolipin

Condensation of Model Lipid Films by Cholesterol: Specific Ion Effects
Martimathin-MA, et al.
Coatings, 9(8), 474-474 (2020)
Assay to Measure Interactions between Purified Drp1 and Synthetic Liposomes
Adachi Y, et al.
Bio-protocol, 7(9) (2017)
Ana Cristina Racca et al.
Frontiers in oncology, 9, 544-544 (2019-07-06)
Tumor cells require high rates of lipid synthesis to support membrane biogenesis for their exacerbated growth. The only two proteins known that activate phospholipid synthesis are Fra-1 and c-Fos, two members of the AP-1 family of transcription factors. These proteins
Koshiki Mino et al.
FEBS letters, 551(1-3), 133-138 (2003-09-11)
O-Acetylserine sulfhydrylase (OASS), a pyridoxal 5'-phosphate (PLP)-dependent enzyme, catalyzes the synthesis of L-cysteine from O-acetyl-L-serine and sulfide. O-Acetyl-L-serine is labile at high temperatures at which hyperthermophilic archaea live. Herein, a study of the substrate specificity of OASS from Aeropyrum pernix
Tetiana Mukhina et al.
The journal of physical chemistry letters, 10(22), 7195-7199 (2019-11-05)
We investigate the interaction between highly charged lipid bilayers in the presence of monovalent counterions. Neutron and X-ray reflectivity experiments show that the water layer between like-charged bilayers is thinner than for zwitterionic lipids, demonstrating the existence of counterintuitive electrostatic
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service