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810198C

Avanti

18:1 NBD PS

Avanti Polar Lipids 810198C

Synonym(s):

1,2-dioleoyl-sn-glycero-3-phospho-L-serine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt)

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About This Item

Empirical Formula (Hill Notation):
C48H85N6O13P
CAS Number:
474943-02-7
Molecular Weight:
985.19
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810198C-1mg)

manufacturer/tradename

Avanti Polar Lipids 810198C

concentration

1 mg/mL (810198C-1mg)

shipped in

dry ice

storage temp.

−20°C

General description

18:1 NBD PS is a fluorescent analog of phosphotidylserine (PS). Phosphotidylserine is considered as a vital lipid and is found in the inner mitochondrial region.

Application

NBD PS might be suitable as a component in premixed lipid solution for V-SNARE (N-ethylmaleimide-sensitive factor attachment protein receptor) proteo-liposomes preparation. It is also suitable for the preparation of control PS/PC (1-palmitoyl-2-oleoylsn-glycero-3-phospho-L-serine/1-palmitoyl-2-oleoyl-sn-glycero-phosphocholine) liposomes.

Biochem/physiol Actions

18:1 NBD PS is useful in labelling mitochondria. Phosphotidylserine is associated with blood clotting mechanism.

Packaging

5 mL Amber Glass Screw Cap Vial (810198C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation.
Yang Y, et al.
Frontiers in immunology (2018)
PS (PhosphatidylSerine) Nature's Brain Booster A Vital Lipid Nutrient For Memory Mood and Stress, 84-84 (2005)
Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor-Derived Peptides for Regulation of Mast Cell Degranulation.
Yang Y, et al.
Frontiers in Immunology (2018)
Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation
Hailey DW, et al.
Cell, 141(4), 656-667 (2010)
Clara Berenguer-Escuder et al.
Journal of clinical medicine, 8(12) (2020-01-01)
Although most cases of Parkinson´s disease (PD) are idiopathic with unknown cause, an increasing number of genes and genetic risk factors have been discovered that play a role in PD pathogenesis. Many of the PD-associated proteins are involved in mitochondrial
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