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810133C

Avanti

18:1-12:0 NBD PC

Avanti Polar Lipids 810133C

Synonym(s):

1-Oleoyl-2-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-sn-Glycero-3-Phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C44H76N5O11P
CAS Number:
190792-36-0
Molecular Weight:
882.07
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810133C-1mg)
pkg of 5 × 1 mL (810133C-5mg)

manufacturer/tradename

Avanti Polar Lipids 810133C

concentration

1 mg/mL (810133C-1mg)
1 mg/mL (810133C-5mg)

lipid type

fluorescent lipids
phospholipids

shipped in

dry ice

storage temp.

−20°C

General description

Phosphatidylcholine (PC) is a prime metabolite in eukaryotes glycerolipid metabolism, mainly synthesized in liver. It is a major element of lipoproteins, bile and lung surfactant. NBD PC contains 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) covalently attached to phosphatidylcholine.

Application

18:1-06:0 NBD PC is suitable for:
  • the generation giant unilamellar vesicles (GUVs) subjected to fluorescence microscopy
  • labelling lipid bilayers formed by vesicle fusion in order to study the lipid distribution by fluorescence microscopy
  • the preparation of phospholipid-coated beads

Biochem/physiol Actions

7-nitrobenz-2-oxa-1,3-diazol-4-yl phosphatidylcholine (NBD PC) functions as a fluorescent analog in biological membranes in order to study the cellular processes.

Packaging

5 mL Amber Glass Screw Cap Vial (810133C-1mg)
5 mL Amber Glass Screw Cap Vial (810133C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH Annex XVII (Restriction List)

CAS No.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Haijia Yu et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(16), 4362-4367 (2016-04-05)
Organelles are in constant communication with each other through exchange of proteins (mediated by trafficking vesicles) and lipids [mediated by both trafficking vesicles and lipid transfer proteins (LTPs)]. It has long been known that vesicle trafficking can be tightly regulated
Muhasin Koyiloth et al.
European biophysics journal : EBJ, 49(2), 163-173 (2020-02-06)
In this study, the SCRM-1 gene from Caenorhabditis elegans was cloned and overexpressed in E. coli to study the biochemical properties of scramblase. This is the first report showing that this scramblase from C. elegans possesses a Ca2+-dependent and head
Hanna Brzeska et al.
The Journal of biological chemistry, 283(46), 32014-32023 (2008-09-06)
The tail of Acanthamoeba myosin IC (AMIC) has a basic region (BR), which contains a putative pleckstrin homology (PH) domain, followed by two Gly/Pro/Ala (GPA)-rich regions separated by a Src homology 3 (SH3) domain. Cryoelectron microscopy had shown that the
Idalia M Sandoval-Jiménez et al.
The Journal of chemical physics, 152(1), 014901-014901 (2020-01-10)
We present a method that takes advantage of the Brownian motion of a colloidal particle to experimentally determine the area stretch modulus of giant liposomes in solution, in regard to the continuum mechanics theory of elasticity. The characteristic parameters of
Non Miyata et al.
The Journal of cell biology, 214(1), 77-88 (2016-06-30)
Phosphatidylethanolamine (PE) is an essential phospholipid for mitochondrial functions and is synthesized mainly by phosphatidylserine (PS) decarboxylase at the mitochondrial inner membrane. In Saccharomyces cerevisiae, PS is synthesized in the endoplasmic reticulum (ER), such that mitochondrial PE synthesis requires PS

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