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P33429

Sigma-Aldrich

4-Phenylpyridine

97%

Synonym(s):

γ-Phenylpyridine, 1-Benzylhydrazine dihydrochloride, p-Phenylpyridine

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About This Item

Empirical Formula (Hill Notation):
C11H9N
CAS Number:
939-23-1
Molecular Weight:
155.20
Beilstein:
110490
EC Number:
213-357-4
MDL number:
MFCD00006420
UNSPSC Code:
12352100
PubChem Substance ID:
24898403
NACRES:
NA.22

Quality Level

100

Assay

97%

form

crystals

bp

274-275 °C (lit.)

mp

69-73 °C (lit.)

SMILES string

c1ccc(cc1)-c2ccncc2

InChI

1S/C11H9N/c1-2-4-10(5-3-1)11-6-8-12-9-7-11/h1-9H

InChI key

JVZRCNQLWOELDU-UHFFFAOYSA-N

Gene Information

human ... MMP3(4314)

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Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315 - H319 - H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R R Ramsay et al.
Biochemical and biophysical research communications, 146(1), 53-60 (1987-07-15)
The neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, an impurity in an illicit drug, is expressed after its oxidation to 1-methyl-4-phenylpyridinium by monoamine oxidase. The pyridinium is concentrated by carrier-mediated transport into the mitochondria where it inhibits NADH dehydrogenase and, hence, ATP synthesis. Some
I Irwin et al.
Life sciences, 40(8), 731-740 (1987-02-23)
Because of the chemical and structural similarity between 4-phenylpyridine (4PP) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), the effects of 4PP alone and in combination with MPTP on striatal dopamine (DA) concentrations were studied in mice. 4PP did not deplete striatal DA, even when
K S Hsu et al.
The Journal of pharmacology and experimental therapeutics, 279(2), 740-747 (1996-11-01)
The effect of L-deprenyl (selegiline) on the excitatory synaptic transmission was characterized in the CA1 neurons of rat hippocampal slices by using a intracellular recording technique. Superfusion of L-deprenyl (0.1-10 microM) reversibly decreased the EPSP, which was evoked by orthodromic
Behavioral and biochemical effects of 4-phenylpyridine, 2-phenylpyridine, and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in rodents.
M N Hassan et al.
Advances in neurology, 53, 219-223 (1990-01-01)
Germano Giuliani et al.
Bioorganic & medicinal chemistry, 19(7), 2242-2251 (2011-03-23)
The quinoline nucleus of the previously described 4-phenylquinoline-3-carboxamides NK(1) receptor ligands 7 has been transformed into either substituted or azole-(i.e., triazole or tetrazole) fused pyridine moieties of compounds 9 and 10, respectively, in order to obtain NK(1) receptor ligands showing
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