900615
(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
≥95%
Synonym(s):
Hydroxyl benzophenone alkyne, Probe building block
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C16H12O3
CAS Number:
Molecular Weight:
252.26
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22
Recommended Products
Quality Level
Assay
≥95%
form
solid
reaction suitability
reaction type: click chemistry
storage temp.
−20°C
Related Categories
Application
(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes
Technology Spotlight: Trifuctional Probe Building Blocks
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids
Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators
γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin
related product
Product No.
Description
Pricing
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Articles
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service