Skip to Content
Merck
All Photos(1)

Documents

436240

Sigma-Aldrich

BRIJ® O20

average Mn ~1,150

Synonym(s):

Polyoxyethylene (20) oleyl ether

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
C18H35(OCH2CH2)nOH, n~20
CAS Number:
Molecular Weight:
1149.53
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

description

non-ionic

Quality Level

mol wt

average Mn ~1,150

technique(s)

cell culture | mammalian: suitable
protein quantification: suitable

mp

25-30 °C (lit.)

HLB

15

InChI

1S/C20H40O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h9-10,21H,2-8,11-20H2,1H3/b10-9-

InChI key

KWVPFECTOKLOBL-KTKRTIGZSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Brij® O20 is a non-ionic surfactant that has an 18 carbon tail with a single double bond and the head contains 20 ethylene oxide moieties. It is polyethoxylated fatty alcohol that is hydrophilic in nature.

Application

Brij® O20 has been used:
  • as a detergent in medium A to prepare single detergent micelle aggregates
  • along with phosphate buffer saline (PBS) solution as the receptor solution for terbinafine (TBF) for in vitro permeation studies of TBF-free base in porcine skin
  • as a detergent to isolate detergent-resistant membranes from the mouse brain and to determine the distribution of major mammalian brain gangliosides, GM1, GD1a, GD1b and GT1b

Legal Information

Brij is a registered trademark of Croda International PLC

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Skin Irrit. 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

464.0 °F - Equilibrium method

Flash Point(C)

> 240 °C - Equilibrium method

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Pulkit Khatri et al.
Journal of pharmaceutical sciences, 107(8), 2198-2207 (2018-04-08)
The study aims to elucidate the mechanism and the role of the molecular structure of surfactants and lipids in the formation of oil-in-water (o/w) self-emulsified nanoemulsions (SENs). The hypothesis is that the overall change of Gibb's free energy (ΔGf) during
Jessica Phelps et al.
Colloids and surfaces. B, Biointerfaces, 87(2), 391-398 (2011-06-28)
In this study, fluid precursor formulations for subcutaneous injection and in situ formation of hexagonal phase gels upon water absorption were developed as a strategy to sustain the release of naltrexone, a drug used for treatment of drug addiction. Precursor
Ahmed S Zidan et al.
International journal of pharmaceutics, 332(1-2), 55-63 (2006-12-16)
Quality by design (QBD) refers to the achievement of certain predictable quality with desired and predetermined specifications. A very useful component of the QBD is the understanding of factors and their interaction effects by a desired set of experiments. The
Yash Kapoor et al.
International journal of pharmaceutics, 361(1-2), 222-229 (2008-06-26)
Cyclosporine A (CyA) is an immunosuppressant drug that is used for treating a variety of ocular diseases and disorders. CyA is commonly delivered via eye drops, which is highly inefficient due to a low bioavailability of less than 5%. The
R B Shah et al.
International journal of pharmaceutics, 341(1-2), 189-194 (2007-05-25)
In the present work, a novel application of ultrasonic measurements is detailed to characterize nano-emulsion formulations as a part of the overall Quality by Design (QbD) goal. Ultrasonic resonator technology (URT) was utilized to measure sound velocity and absorption of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service