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Merck

569250-U

Supelco

Discovery® HS C18 (3 µm) HPLC Columns

L × I.D. 5 cm × 4.6 mm, HPLC Column

Synonym(e):

Discovery RP18 HPLC Column

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About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Discovery® HS C18 HPLC-Säule, 3 μm particle size, L × I.D. 5 cm × 4.6 mm

Materialien

stainless steel column

Qualitätsniveau

Agentur

suitable for USP L1

Produktlinie

Discovery®

Leistungsmerkmale

endcapped

Hersteller/Markenname

Discovery®

Verpackung

1 ea of

Kennzeichnungsgrad

20% Carbon loading

Parameter

≤70 °C temp. range
400 bar pressure (5801 psi)

Methode(n)

HPLC: suitable
LC/MS: suitable

L × ID

5 cm × 4.6 mm

Oberflächenbereich

300 m2/g

Oberflächendeckung

3.2 μmol/m2

Verunreinigungen

<10 ppm metals

Matrix

silica gel, high purity, spherical particle platform
fully porous particle

Aktive Matrixgruppe

C18 (octadecyl) phase

Partikelgröße

3 μm

Porengröße

120 Å

operating pH range

2-8

Anwendung(en)

food and beverages

Trenntechnik

reversed phase

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Verwandte Kategorien

Anwendung


  • A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This study developed a robust RP-HPLC method to determine molnupiravir in various nanoformulations, showcasing its potential application in permeability studies and ensuring drug stability (Reçber et al., 2022) (Reçber et al., 2022).

  • Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: This research presented an HPLC-UV method for analyzing terizidone in plasma, facilitating its use in pharmacokinetic studies of patients with drug-resistant tuberculosis (Mulubwa and Mugabo, 2018) (Mulubwa and Mugabo, 2018).

  • Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: The study optimized an LC method for quantifying doxorubicin in plasma and urine, crucial for pharmacokinetic, biomedical, and drug monitoring therapy applications (Maliszewska et al., 2018) (Maliszewska et al., 2018).

Leistungsmerkmale und Vorteile

  • Stabile LC-MS-Trennungen mit extrem geringem Bluten
  • Im analytischen bis präparativen Maßstab erhältlich
  • Äußerst stabil, sichert außergewöhnliche Reproduzierbarkeit von Lauf zu Lauf und von Säule zu Säule
  • Höhere Hydrophobie, für eine bessere Trennung anspruchsvoller Verbindungen

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Rechtliche Hinweise

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Abad Khan et al.
Talanta, 84(3), 789-801 (2011-04-13)
A new, simple, economical and validated high-performance liquid chromatography linked with electrochemical detector (HPLC-ECD) method has been developed and optimized for different experimental parameters to analyze the most common monothiols and disulfide (cystine, cysteine, homocysteine, methionine, reduced (GSH) and oxidized
Awantika Singh et al.
Rapid communications in mass spectrometry : RCM, 29(6), 485-496 (2015-07-15)
Adhatoda beddomei and Adhatoda vasica are popular Ayurvedic medicinal plants in India, belonging to the family Acanthaceae. Tricyclic quinazoline alkaloids are found to be the most abundant in these plants which are responsible for broad-spectrum medicinal properties. This study aims
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Ismail Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1033-1034, 261-270 (2016-09-07)
A simple, economical, fast, and sensitive RP-HPLC-UV method has been developed for the simultaneous quantification of Sorafenib and paclitaxel in biological samples and formulations using piroxicam as an internal standard. The experimental conditions were optimized and method was validated according
Lucie Zelena et al.
Journal of pharmaceutical and biomedical analysis, 137, 70-77 (2017-01-17)
Efavirenz is an antiretroviral drug used in the treatment of HIV-positive patients. A simple, fast and sensitive high-performance liquid chromatography (HPLC) method was developed in order to determine efavirenz in three types of samples provided from pharmacokinetic studies. The analysis

Verwandter Inhalt

HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.

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